CCDC66 (coiled-coil domain containing 66)

2017-10-01  

Identity

HGNC
LOCATION
3p14.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 285331
HGNC: 27709
Ensembl: ENSG00000180376

Variants:

dbSNP: 285331
ClinVar: 285331
TCGA: ENSG00000180376
COSMIC: CCDC66

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180376ENST00000326595A2RUB6
ENSG00000180376ENST00000341455F8WCY0
ENSG00000180376ENST00000394672A2RUB6
ENSG00000180376ENST00000422222C9JYB8
ENSG00000180376ENST00000422788F8WB87
ENSG00000180376ENST00000434467F2Z2K6
ENSG00000180376ENST00000439445F2Z2K6
ENSG00000180376ENST00000471681F8WDJ0

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378527492024CCDC66 mutations are associated with high myopia through affected cell mitosis.0
378527492024CCDC66 mutations are associated with high myopia through affected cell mitosis.0
366064242023CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins.5
366064242023CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins.5
350697932022Circular RNA CCDC66 Improves Murine Double Minute 4 (MDM4) Expression through Targeting miR-370 in Colorectal Cancer.5
350697932022Circular RNA CCDC66 Improves Murine Double Minute 4 (MDM4) Expression through Targeting miR-370 in Colorectal Cancer.5
342528822021Circular RNA circCCDC66 promotes glioma proliferation by acting as a ceRNA for miR-320a to regulate FOXM1 expression.10
342528822021Circular RNA circCCDC66 promotes glioma proliferation by acting as a ceRNA for miR-320a to regulate FOXM1 expression.10
319974042020Circular RNA CCDC66 facilitates abdominal aortic aneurysm through the overexpression of CCDC66.18
322530302020CircRNACCDC66 regulates cisplatin resistance in gastric cancer via the miR-618/BCL2 axis.27
319974042020Circular RNA CCDC66 facilitates abdominal aortic aneurysm through the overexpression of CCDC66.18
322530302020CircRNACCDC66 regulates cisplatin resistance in gastric cancer via the miR-618/BCL2 axis.27
304439882019Circular RNA CCDC66 targets DCX to regulate cell proliferation and migration by sponging miR-488-3p in Hirschsprung's disease.16
311732872019Circ-CCDC66 accelerates proliferation and invasion of gastric cancer via binding to miRNA-1238-3p.6
315827662019Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors.19

Citation

Dessen P

CCDC66 (coiled-coil domain containing 66)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57141/ccdc66-(coiled-coil-domain-containing-66)