SLC16A2 (solute carrier family 16 member 2)

2017-10-01  

Identity

HGNC
LOCATION
Xq13.2
LOCUSID
ALIAS
AHDS,DXS128,DXS128E,MCT 7,MCT 8,MCT7,MCT8,MRX22,XPCT
FUSION GENES

Other Information

Locus ID:

NCBI: 6567
MIM: 300095
HGNC: 10923
Ensembl: ENSG00000147100

Variants:

dbSNP: 6567
ClinVar: 6567
TCGA: ENSG00000147100
COSMIC: SLC16A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147100ENST00000587091P36021
ENSG00000147100ENST00000590447K7ELT4
ENSG00000147100ENST00000636771A0A1B0GVB4

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Thyroid hormone signaling pathwayKEGGhsa04919
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of vitamins, nucleosides, and related moleculesREACTOMER-HSA-425397
Transport of organic anionsREACTOMER-HSA-879518

References

Pubmed IDYearTitleCitations
383769502024Impaired T3 uptake and action in MCT8-deficient cerebral organoids underlie Allan-Herndon-Dudley syndrome.2
386540932024Spatiotemporal expression of thyroid hormone transporter MCT8 and THRA mRNA in human cerebral organoids recapitulating first trimester cortex development.2
383769502024Impaired T3 uptake and action in MCT8-deficient cerebral organoids underlie Allan-Herndon-Dudley syndrome.2
386540932024Spatiotemporal expression of thyroid hormone transporter MCT8 and THRA mRNA in human cerebral organoids recapitulating first trimester cortex development.2
365952092023Role and Clinical Significance of Monocarboxylate Transporter 8 (MCT8) During Pregnancy.1
368346212023Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Pyramidal Neurons and Interneurons in the Adult Motor Cortex of Human and Macaque Brain.6
372985942023Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Projection Neurons and Interneurons of Basal Ganglia and Motor Thalamus in the Adult Human and Macaque Brains.2
365952092023Role and Clinical Significance of Monocarboxylate Transporter 8 (MCT8) During Pregnancy.1
368346212023Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Pyramidal Neurons and Interneurons in the Adult Motor Cortex of Human and Macaque Brain.6
372985942023Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Projection Neurons and Interneurons of Basal Ganglia and Motor Thalamus in the Adult Human and Macaque Brains.2
340972512021The tissue expression of MCT3, MCT8, and MCT9 genes in women with breast cancer.13
345395762021Monocarboxylate Transporter 8 Deficiency: From Pathophysiological Understanding to Therapy Development.11
340972512021The tissue expression of MCT3, MCT8, and MCT9 genes in women with breast cancer.13
345395762021Monocarboxylate Transporter 8 Deficiency: From Pathophysiological Understanding to Therapy Development.11
318204242020Single Nucleotide Polymorphisms in Thyroid Hormone Transporter Genes MCT8, MCT10 and Deiodinase DIO2 Contribute to Inter-Individual Variance of Executive Functions and Personality Traits.6

Citation

Dessen P

SLC16A2 (solute carrier family 16 member 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57153/slc16a2-(solute-carrier-family-16-member-2)