USP51 (ubiquitin specific peptidase 51)

2017-10-01  

Identity

HGNC
LOCATION
Xp11.21
LOCUSID

Other Information

Locus ID:

NCBI: 158880
HGNC: 23086
Ensembl: ENSG00000247746

Variants:

dbSNP: 158880
ClinVar: 158880
TCGA: ENSG00000247746
COSMIC: USP51

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000247746ENST00000500968Q70EK9
ENSG00000247746ENST00000586165A0A1B0GVA6

Expression (GTEx)

0
1
2
3
4
5

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
358564032023The role of USP51 in attenuating chemosensitivity of lung cancer cells to cisplatin by regulating DNA damage response.1
374226322023USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1.1
378169992023USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A.3
358564032023The role of USP51 in attenuating chemosensitivity of lung cancer cells to cisplatin by regulating DNA damage response.1
374226322023USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1.1
378169992023USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A.3
322960272020CDK4/6 inhibition blocks cancer metastasis through a USP51-ZEB1-dependent deubiquitination mechanism.30
322960272020CDK4/6 inhibition blocks cancer metastasis through a USP51-ZEB1-dependent deubiquitination mechanism.30
270839982016USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response.47
271329402016ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.72
270839982016USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response.47
271329402016ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.72

Citation

Dessen P

USP51 (ubiquitin specific peptidase 51)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57157/usp51-(ubiquitin-specific-peptidase-51)