Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64838
MIM: 611905
HGNC: 20239
Ensembl: ENSG00000115226
Variants:
dbSNP: 64838
ClinVar: 64838
TCGA: ENSG00000115226
COSMIC: FNDC4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115226 | ENST00000264703 | Q9H6D8 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38181585 | 2024 | FNDC4 reduces inflammation, proliferation, invasion and migration of rheumatoid synovial cells by inhibiting CCL2/ERK signaling. | 0 |
| 38181585 | 2024 | FNDC4 reduces inflammation, proliferation, invasion and migration of rheumatoid synovial cells by inhibiting CCL2/ERK signaling. | 0 |
| 35521900 | 2022 | Irisin and the fibronectin type III domain-containing family: structure, signaling and role in female reproduction. | 4 |
| 35521900 | 2022 | Irisin and the fibronectin type III domain-containing family: structure, signaling and role in female reproduction. | 4 |
| 34016966 | 2021 | Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue. | 17 |
| 34465884 | 2021 | FNDC4 and FNDC5 reduce SARS-CoV-2 entry points and spike glycoprotein S1-induced pyroptosis, apoptosis, and necroptosis in human adipocytes. | 28 |
| 34016966 | 2021 | Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue. | 17 |
| 34465884 | 2021 | FNDC4 and FNDC5 reduce SARS-CoV-2 entry points and spike glycoprotein S1-induced pyroptosis, apoptosis, and necroptosis in human adipocytes. | 28 |
| 32407726 | 2020 | FNDC4, a novel adipokine that reduces lipogenesis and promotes fat browning in human visceral adipocytes. | 23 |
| 32407726 | 2020 | FNDC4, a novel adipokine that reduces lipogenesis and promotes fat browning in human visceral adipocytes. | 23 |
| 27066907 | 2016 | FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice. | 40 |
| 27066907 | 2016 | FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice. | 40 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
Citation
Dessen P
FNDC4 (fibronectin type III domain containing 4)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57161/fndc4-(fibronectin-type-iii-domain-containing-4)
