Identity
HGNC
LOCATION
14q22.1
LOCUSID
ALIAS
C14orf166,CGI-99,CGI99,CLE,CLE7,LCRP369,RLLM1,hCLE,hCLE1
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51637
MIM: 610858
HGNC: 23169
Ensembl: ENSG00000087302
Variants:
dbSNP: 51637
ClinVar: 51637
TCGA: ENSG00000087302
COSMIC: RTRAF
RNA/Proteins
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| tRNA processing | REACTOME | R-HSA-72306 |
| tRNA processing in the nucleus | REACTOME | R-HSA-6784531 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37265372 | 2023 | An in silico prediction of interaction models of influenza A virus PA and human C14orf166 protein from yeast-two-hybrid screening data. | 0 |
| 37265372 | 2023 | An in silico prediction of interaction models of influenza A virus PA and human C14orf166 protein from yeast-two-hybrid screening data. | 0 |
| 34854379 | 2021 | Molecular architecture of the human tRNA ligase complex. | 15 |
| 34854379 | 2021 | Molecular architecture of the human tRNA ligase complex. | 15 |
| 28040436 | 2017 | FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression. | 14 |
| 28040436 | 2017 | FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression. | 14 |
| 26219895 | 2016 | C14ORF166 overexpression is associated with pelvic lymph node metastasis and poor prognosis in uterine cervical cancer. | 10 |
| 26864902 | 2016 | hCLE/C14orf166, a cellular protein required for viral replication, is incorporated into influenza virus particles. | 5 |
| 26883017 | 2016 | C14orf166 overexpression correlates with tumor progression and poor prognosis of breast cancer. | 1 |
| 26905879 | 2016 | C14orf166 is a high-risk biomarker for bladder cancer and promotes bladder cancer cell proliferation. | 5 |
| 26219895 | 2016 | C14ORF166 overexpression is associated with pelvic lymph node metastasis and poor prognosis in uterine cervical cancer. | 10 |
| 26864902 | 2016 | hCLE/C14orf166, a cellular protein required for viral replication, is incorporated into influenza virus particles. | 5 |
| 26883017 | 2016 | C14orf166 overexpression correlates with tumor progression and poor prognosis of breast cancer. | 1 |
| 26905879 | 2016 | C14orf166 is a high-risk biomarker for bladder cancer and promotes bladder cancer cell proliferation. | 5 |
| 25964093 | 2015 | Overexpression of chromosome 14 open reading frame 166 correlates with disease progression and poorer prognosis in human NPC. | 3 |
Citation
Dessen P
RTRAF (RNA transcription, translation and transport factor)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57165/rtraf-(rna-transcription-translation-and-transport-factor)
