TCIM (transcriptional and immune response regulator)

2017-10-01  

Identity

HGNC
LOCATION
8p11.21
LOCUSID
ALIAS
C8orf4,TC-1,TC1

Other Information

Locus ID:

NCBI: 56892
MIM: 607702
HGNC: 1357
Ensembl: ENSG00000176907

Variants:

dbSNP: 56892
ClinVar: 56892
TCGA: ENSG00000176907
COSMIC: TCIM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176907ENST00000315792Q9NR00

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
310260672019H19/miR-30a/C8orf4 axis modulates the adipogenic differentiation process in human adipose tissue-derived mesenchymal stem cells.18
310810982019Correlations of ultrasound and pathological features of thyroid carcinoma with TC-1 mRNA and protein expression.0
313740652019Association of C8orf4 expression with its methylation status, aberrant β-catenin expression, and the development of cervical squamous cell carcinoma.2
310260672019H19/miR-30a/C8orf4 axis modulates the adipogenic differentiation process in human adipose tissue-derived mesenchymal stem cells.18
310810982019Correlations of ultrasound and pathological features of thyroid carcinoma with TC-1 mRNA and protein expression.0
313740652019Association of C8orf4 expression with its methylation status, aberrant β-catenin expression, and the development of cervical squamous cell carcinoma.2
298428862018Circular RNA circZFR contributes to papillary thyroid cancer cell proliferation and invasion by sponging miR-1261 and facilitating C8orf4 expression.60
298428862018Circular RNA circZFR contributes to papillary thyroid cancer cell proliferation and invasion by sponging miR-1261 and facilitating C8orf4 expression.60
267444102016Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis.36
267444102016Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis.36
258698792015The high expression of TC1 (C8orf4) was correlated with the expression of β-catenin and cyclin D1 and the progression of squamous cell carcinomas of the tongue.9
259857372015C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling.72
258698792015The high expression of TC1 (C8orf4) was correlated with the expression of β-catenin and cyclin D1 and the progression of squamous cell carcinomas of the tongue.9
259857372015C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling.72
249413472014TC-1 overexpression promotes cell proliferation in human non-small cell lung cancer that can be inhibited by PD173074.8

Citation

Dessen P

TCIM (transcriptional and immune response regulator)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57173/tcim-(transcriptional-and-immune-response-regulator)