Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27445
MIM: 604918
HGNC: 13406
Ensembl: ENSG00000186472
Variants:
dbSNP: 27445
ClinVar: 27445
TCGA: ENSG00000186472
COSMIC: PCLO
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Insulin secretion | KEGG | hsa04911 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32493491 | 2020 | No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease. | 4 |
| 32493491 | 2020 | No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease. | 4 |
| 28240412 | 2017 | A 7q21.11 microdeletion presenting with apparent intellectual disability without epilepsy. | 2 |
| 28263981 | 2017 | Piccolo mediates EGFR signaling and acts as a prognostic biomarker in esophageal squamous cell carcinoma. | 20 |
| 28540843 | 2017 | Genome-Wide Significance for PCLO as a Gene for Major Depressive Disorder. | 14 |
| 28240412 | 2017 | A 7q21.11 microdeletion presenting with apparent intellectual disability without epilepsy. | 2 |
| 28263981 | 2017 | Piccolo mediates EGFR signaling and acts as a prognostic biomarker in esophageal squamous cell carcinoma. | 20 |
| 28540843 | 2017 | Genome-Wide Significance for PCLO as a Gene for Major Depressive Disorder. | 14 |
| 26391493 | 2016 | GWAS-identified risk variants for major depressive disorder: Preliminary support for an association with late-life depressive symptoms and brain structural alterations. | 9 |
| 27776345 | 2016 | Quantitative proteomics reveals Piccolo as a candidate serological correlate of recovery from Guillain-Barré syndrome. | 4 |
| 26391493 | 2016 | GWAS-identified risk variants for major depressive disorder: Preliminary support for an association with late-life depressive symptoms and brain structural alterations. | 9 |
| 27776345 | 2016 | Quantitative proteomics reveals Piccolo as a candidate serological correlate of recovery from Guillain-Barré syndrome. | 4 |
| 25636086 | 2015 | Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity. | 87 |
| 25817861 | 2015 | The Piccolo Intronic Single Nucleotide Polymorphism rs13438494 Regulates Dopamine and Serotonin Uptake and Shows Associations with Dependence-Like Behavior in Genomic Association Study. | 4 |
| 25832664 | 2015 | Loss of PCLO function underlies pontocerebellar hypoplasia type III. | 21 |
Citation
Dessen P
PCLO (piccolo presynaptic cytomatrix protein)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57175/pclo-(piccolo-presynaptic-cytomatrix-protein)
