Identity
HGNC
LOCATION
Xq21.1
LOCUSID
ALIAS
HEL-S-115,SH3BGR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6451
MIM: 300190
HGNC: 10823
Ensembl: ENSG00000131171
Variants:
dbSNP: 6451
ClinVar: 6451
TCGA: ENSG00000131171
COSMIC: SH3BGRL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000131171 | ENST00000373212 | O75368 |
| ENSG00000131171 | ENST00000373212 | V9HW48 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33953316 | 2023 | Distinct functions of CAR-T cells possessing a dectin-1 intracellular signaling domain. | 4 |
| 33953316 | 2023 | Distinct functions of CAR-T cells possessing a dectin-1 intracellular signaling domain. | 4 |
| 34870550 | 2022 | Adaptor SH3BGRL drives autophagy-mediated chemoresistance through promoting PIK3C3 translation and ATG12 stability in breast cancers. | 6 |
| 34963436 | 2022 | Decitabine Enhances Acute Myeloid Leukemia Cell Apoptosis through SH3BGRL Upregulation. | 0 |
| 34870550 | 2022 | Adaptor SH3BGRL drives autophagy-mediated chemoresistance through promoting PIK3C3 translation and ATG12 stability in breast cancers. | 6 |
| 34963436 | 2022 | Decitabine Enhances Acute Myeloid Leukemia Cell Apoptosis through SH3BGRL Upregulation. | 0 |
| 34331014 | 2021 | Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation. | 5 |
| 34331014 | 2021 | Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation. | 5 |
| 28679293 | 2018 | SH3BGRL as a novel prognostic biomarker is down-regulated in acute myeloid leukemia. | 7 |
| 28679293 | 2018 | SH3BGRL as a novel prognostic biomarker is down-regulated in acute myeloid leukemia. | 7 |
| 26455318 | 2016 | Dual-faced SH3BGRL: oncogenic in mice, tumor suppressive in humans. | 12 |
| 26455318 | 2016 | Dual-faced SH3BGRL: oncogenic in mice, tumor suppressive in humans. | 12 |
| 20532202 | 2010 | Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes. | 42 |
| 20532202 | 2010 | Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes. | 42 |
| 16186799 | 2006 | The suppression of SH3BGRL is important for v-Rel-mediated transformation. | 19 |
Citation
Dessen P
SH3BGRL (SH3 domain binding glutamate rich protein like)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57176/sh3bgrl-(sh3-domain-binding-glutamate-rich-protein-like)
