Identity
HGNC
LOCATION
2q31.1
LOCUSID
ALIAS
CYB561A2,DCYTB,FRRS3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79901
MIM: 605745
HGNC: 20797
Ensembl: ENSG00000071967
Variants:
dbSNP: 79901
ClinVar: 79901
TCGA: ENSG00000071967
COSMIC: CYBRD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000071967 | ENST00000321348 | Q53TN4 |
| ENSG00000071967 | ENST00000375252 | Q53TN4 |
| ENSG00000071967 | ENST00000409484 | Q53TN4 |
| ENSG00000071967 | ENST00000445146 | C9JML1 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Mineral absorption | KEGG | ko04978 |
| Mineral absorption | KEGG | hsa04978 |
| Transmembrane transport of small molecules | REACTOME | R-HSA-382551 |
| Iron uptake and transport | REACTOME | R-HSA-917937 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36593242 | 2023 | DDX17 induces epithelial-mesenchymal transition and metastasis through the miR-149-3p/CYBRD1 pathway in colorectal cancer. | 7 |
| 36593242 | 2023 | DDX17 induces epithelial-mesenchymal transition and metastasis through the miR-149-3p/CYBRD1 pathway in colorectal cancer. | 7 |
| 34714955 | 2021 | miR-423-3p activates FAK signaling pathway to drive EMT process and tumor growth in lung adenocarcinoma through targeting CYBRD1. | 7 |
| 34714955 | 2021 | miR-423-3p activates FAK signaling pathway to drive EMT process and tumor growth in lung adenocarcinoma through targeting CYBRD1. | 7 |
| 30544799 | 2018 | Iron Supplements Containing Lactobacillus plantarum 299v Increase Ferric Iron and Up-regulate the Ferric Reductase DCYTB in Human Caco-2/HT29 MTX Co-Cultures. | 15 |
| 30544799 | 2018 | Iron Supplements Containing Lactobacillus plantarum 299v Increase Ferric Iron and Up-regulate the Ferric Reductase DCYTB in Human Caco-2/HT29 MTX Co-Cultures. | 15 |
| 27439017 | 2017 | Analysis of polymorphism and hepatic expression of duodenal cytochrome b in chronic hepatitis C. | 3 |
| 28270217 | 2017 | DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms. | 19 |
| 28937159 | 2017 | Duodenal cytochrome b (Cybrd1) ferric reductase functional studies in cells. | 5 |
| 27439017 | 2017 | Analysis of polymorphism and hepatic expression of duodenal cytochrome b in chronic hepatitis C. | 3 |
| 28270217 | 2017 | DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms. | 19 |
| 28937159 | 2017 | Duodenal cytochrome b (Cybrd1) ferric reductase functional studies in cells. | 5 |
| 23012398 | 2013 | Iron homeostasis in porphyria cutanea tarda: mutation analysis of promoter regions of CP, CYBRD1, HAMP and SLC40A1. | 1 |
| 23012398 | 2013 | Iron homeostasis in porphyria cutanea tarda: mutation analysis of promoter regions of CP, CYBRD1, HAMP and SLC40A1. | 1 |
| 22773607 | 2012 | CYBRD1 as a modifier gene that modulates iron phenotype in HFE p.C282Y homozygous patients. | 15 |
Citation
Dessen P
CYBRD1 (cytochrome b reductase 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57205/cybrd1-(cytochrome-b-reductase-1)
