Identity
HGNC
LOCATION
6q25.3
LOCUSID
ALIAS
CW-1,TCTEL1,TCTEX1,tctex-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6993
MIM: 601554
HGNC: 11697
Ensembl: ENSG00000146425
Variants:
dbSNP: 6993
ClinVar: 6993
TCGA: ENSG00000146425
COSMIC: DYNLT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000146425 | ENST00000367089 | P63172 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32995988 | 2021 | DYNLT1 gene expression is downregulated in whole blood of patients at different Huntington's disease stages. | 2 |
| 32995988 | 2021 | DYNLT1 gene expression is downregulated in whole blood of patients at different Huntington's disease stages. | 2 |
| 31382319 | 2019 | Relationship between DYNLT1 and Beclin1 expression and the fertilising potential of human spermatozoa. | 4 |
| 31382319 | 2019 | Relationship between DYNLT1 and Beclin1 expression and the fertilising potential of human spermatozoa. | 4 |
| 29406369 | 2018 | Silencing of Tctex1 impairs autophagy lysosomal degradation of α-synuclein and cell viability. | 0 |
| 29535305 | 2018 | Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination. | 28 |
| 29693725 | 2018 | Tctex-1, a novel interaction partner of Kidney Injury Molecule-1, is required for efferocytosis. | 3 |
| 30091292 | 2018 | MAP4 regulates Tctex-1 and promotes the migration of epidermal cells in hypoxia. | 5 |
| 29406369 | 2018 | Silencing of Tctex1 impairs autophagy lysosomal degradation of α-synuclein and cell viability. | 0 |
| 29535305 | 2018 | Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination. | 28 |
| 29693725 | 2018 | Tctex-1, a novel interaction partner of Kidney Injury Molecule-1, is required for efferocytosis. | 3 |
| 30091292 | 2018 | MAP4 regulates Tctex-1 and promotes the migration of epidermal cells in hypoxia. | 5 |
| 28607034 | 2017 | Tctex-1 controls ciliary resorption by regulating branched actin polymerization and endocytosis. | 23 |
| 28970129 | 2017 | Tctex1 plays a key role in the α-synuclein autophagy lysosomal degradation pathway. | 1 |
| 28607034 | 2017 | Tctex-1 controls ciliary resorption by regulating branched actin polymerization and endocytosis. | 23 |
Citation
Dessen P
DYNLT1 (dynein light chain Tctex-type 1)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57209/dynlt1-(dynein-light-chain-tctex-type-1)
