Identity
HGNC
LOCATION
19q13.32
LOCUSID
ALIAS
Pta1,SPK,SYM
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8189
MIM: 602388
HGNC: 22935
Ensembl: ENSG00000125755
Variants:
dbSNP: 8189
ClinVar: 8189
TCGA: ENSG00000125755
COSMIC: SYMPK
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29167270 | 2018 | UbiA prenyltransferase domain-containing protein-1 modulates HMG-CoA reductase degradation to coordinate synthesis of sterol and nonsterol isoprenoids. | 15 |
| 30032159 | 2018 | Rab11 Functions as an Oncoprotein via Nuclear Factor kappa B (NF-κB) Signaling Pathway in Human Bladder Carcinoma. | 4 |
| 29167270 | 2018 | UbiA prenyltransferase domain-containing protein-1 modulates HMG-CoA reductase degradation to coordinate synthesis of sterol and nonsterol isoprenoids. | 15 |
| 30032159 | 2018 | Rab11 Functions as an Oncoprotein via Nuclear Factor kappa B (NF-κB) Signaling Pathway in Human Bladder Carcinoma. | 4 |
| 28295283 | 2017 | Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans. | 14 |
| 28630428 | 2017 | Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner. | 2 |
| 28295283 | 2017 | Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans. | 14 |
| 28630428 | 2017 | Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner. | 2 |
| 25921069 | 2015 | Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors. | 29 |
| 25921069 | 2015 | Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors. | 29 |
| 23994619 | 2013 | Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells. | 1 |
| 23994619 | 2013 | Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells. | 1 |
| 22218735 | 2012 | Expression and distribution of symplekin regulates the assembly and function of the epithelial tight junction. | 6 |
| 22218735 | 2012 | Expression and distribution of symplekin regulates the assembly and function of the epithelial tight junction. | 6 |
| 20133805 | 2010 | Symplekin promotes tumorigenicity by up-regulating claudin-2 expression. | 43 |
Citation
Dessen P
SYMPK (symplekin)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/gene/57217/sympk-(symplekin)
