GPR135 (G protein-coupled receptor 135)

2017-11-01  

Identity

HGNC
GPR135
LOCATION
14q23.1
LOCUSID
64582
ALIAS
HUMNPIIY20

Other Information

Locus ID:

NCBI: 64582
MIM: 607970
HGNC: 19991
Ensembl: ENSG00000181619

Variants:

dbSNP: 64582
ClinVar: 64582
TCGA: ENSG00000181619
COSMIC: GPR135

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181619ENST00000395116Q8IZ08
ENSG00000181619ENST00000481661Q8IZ08

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
287227702017Asbestos-associated genome-wide DNA methylation changes in lung cancer.21
288275382017Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT(2) receptor reciprocally modulate their signaling functions.9
287227702017Asbestos-associated genome-wide DNA methylation changes in lung cancer.21
288275382017Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT(2) receptor reciprocally modulate their signaling functions.9
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.17
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.17

Citation

Dessen P

GPR135 (G protein-coupled receptor 135)

Atlas Genet Cytogenet Oncol Haematol. 2017-11-01

Online version: http://atlasgeneticsoncology.org/gene/57228/gpr135-(g-protein-coupled-receptor-135)