DAPL1 (death associated protein like 1)

2017-11-01  

Identity

HGNC
LOCATION
2q24.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 92196
HGNC: 21490
Ensembl: ENSG00000163331

Variants:

dbSNP: 92196
ClinVar: 92196
TCGA: ENSG00000163331
COSMIC: DAPL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163331ENST00000309950A0PJW8
ENSG00000163331ENST00000309950M1E9T5
ENSG00000163331ENST00000343761H0Y3U5
ENSG00000163331ENST00000409042B8ZZC6
ENSG00000163331ENST00000621326M1EA23

Expression (GTEx)

0
50
100
150
200
250

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208006032010Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.12
256809342015A Candidate Gene Association Study Identifies DAPL1 as a Female-Specific Susceptibility Locus for Age-Related Macular Degeneration (AMD).9
283348462017DAPL1, a susceptibility locus for age-related macular degeneration, acts as a novel suppressor of cell proliferation in the retinal pigment epithelium.2
291711812018Regulation of cell proliferation in the retinal pigment epithelium: Differential regulation of the death-associated protein like-1 DAPL1 by alternative MITF splice forms.2

Citation

Dessen P

DAPL1 (death associated protein like 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-11-01

Online version: http://atlasgeneticsoncology.org/gene/57234/dapl1-(death-associated-protein-like-1)