Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 111
MIM: 600293
HGNC: 236
Ensembl: ENSG00000173175
Variants:
dbSNP: 111
ClinVar: 111
TCGA: ENSG00000173175
COSMIC: ADCY5
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA172 | GNAI1 | Gene | Pathway | associated | |||
| PA173 | GNAI3 | Gene | Pathway | associated | |||
| PA175 | GNAS | Gene | Pathway | associated | |||
| PA24347 | GNAI2 | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36610259 | 2023 | Deep brain stimulation effect in genetic dyskinetic cerebral palsy: The case of ADCY5- related disease. | 0 |
| 36610259 | 2023 | Deep brain stimulation effect in genetic dyskinetic cerebral palsy: The case of ADCY5- related disease. | 0 |
| 35288007 | 2022 | Mutation of ADCY5 gene in patients with Meige syndrome. | 1 |
| 36233117 | 2022 | Association of MARC1, ADCY5, and BCO1 Variants with the Lipid Profile, Suggests an Additive Effect for Hypertriglyceridemia in Mexican Adult Men. | 2 |
| 35288007 | 2022 | Mutation of ADCY5 gene in patients with Meige syndrome. | 1 |
| 36233117 | 2022 | Association of MARC1, ADCY5, and BCO1 Variants with the Lipid Profile, Suggests an Additive Effect for Hypertriglyceridemia in Mexican Adult Men. | 2 |
| 33493164 | 2021 | Gαi1 inhibition mechanism of ATP-bound adenylyl cyclase type 5. | 4 |
| 33684620 | 2021 | By inhibiting ADCY5, miR-18a-3p promotes osteoporosis and possibly contributes to spinal fracture. | 2 |
| 33704598 | 2021 | Homozygous ADCY5 mutation causes early-onset movement disorder with severe intellectual disability. | 4 |
| 33934385 | 2021 | An Update on the Phenotype, Genotype and Neurobiology of ADCY5-Related Disease. | 16 |
| 34169461 | 2021 | Association of diabetes-related variants in ADCY5 and CDKAL1 with neonatal insulin, C-peptide, and birth weight. | 0 |
| 33493164 | 2021 | Gαi1 inhibition mechanism of ATP-bound adenylyl cyclase type 5. | 4 |
| 33684620 | 2021 | By inhibiting ADCY5, miR-18a-3p promotes osteoporosis and possibly contributes to spinal fracture. | 2 |
| 33704598 | 2021 | Homozygous ADCY5 mutation causes early-onset movement disorder with severe intellectual disability. | 4 |
| 33934385 | 2021 | An Update on the Phenotype, Genotype and Neurobiology of ADCY5-Related Disease. | 16 |
Citation
Dessen P
ADCY5 (adenylate cyclase 5)
Atlas Genet Cytogenet Oncol Haematol. 2017-11-01
Online version: http://atlasgeneticsoncology.org/gene/57259/adcy5-(adenylate-cyclase-5)
