ASB3 (ankyrin repeat and SOCS box containing 3)

2017-11-01  

Identity

HGNC
LOCATION
2p16.2
LOCUSID
ALIAS
ASB-3
FUSION GENES

Other Information

Locus ID:

NCBI: 51130
MIM: 605760
HGNC: 16013
Ensembl: ENSG00000115239

Variants:

dbSNP: 51130
ClinVar: 51130
TCGA: ENSG00000115239
COSMIC: ASB3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115239ENST00000263634Q9Y575
ENSG00000115239ENST00000394717Q9Y575
ENSG00000115239ENST00000406053H7BYZ6
ENSG00000115239ENST00000406625Q9Y575
ENSG00000115239ENST00000406687Q9Y575

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
158998732005Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor II.26
255621072015Genome-wide association study of short-acting β2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3.11
280882282017The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells.7

Citation

Dessen P

ASB3 (ankyrin repeat and SOCS box containing 3)

Atlas Genet Cytogenet Oncol Haematol. 2017-11-01

Online version: http://atlasgeneticsoncology.org/gene/57260/asb3-(ankyrin-repeat-and-socs-box-containing-3)