TRIM56 (tripartite motif containing 56)

2018-02-01  

Identity

HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
RNF109
FUSION GENES

Other Information

Locus ID:

NCBI: 81844
MIM: 616996
HGNC: 19028
Ensembl: ENSG00000169871

Variants:

dbSNP: 81844
ClinVar: 81844
TCGA: ENSG00000169871
COSMIC: TRIM56

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169871ENST00000306085Q9BRZ2
ENSG00000169871ENST00000412507C9JI91
ENSG00000169871ENST00000467847A0A0D9SF19

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Cytosolic sensors of pathogen-associated DNAREACTOMER-HSA-1834949
Regulation of innate immune responses to cytosolic DNAREACTOMER-HSA-3134975

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383480472024TRIM56: a promising prognostic immune biomarker for glioma revealed by pan-cancer and single-cell analysis.0
385560842024Key roles for phosphorylation and the Coiled-coil domain in TRIM56-mediated positive regulation of TLR3-TRIF-dependent innate immunity.1
383480472024TRIM56: a promising prognostic immune biomarker for glioma revealed by pan-cancer and single-cell analysis.0
385560842024Key roles for phosphorylation and the Coiled-coil domain in TRIM56-mediated positive regulation of TLR3-TRIF-dependent innate immunity.1
369024782023The Functions of TRIM56 in Antiviral Innate Immunity and Tumorigenesis.8
369024782023The Functions of TRIM56 in Antiviral Innate Immunity and Tumorigenesis.8
350622932022Impaired Antiviral Responses to Extracellular Double-Stranded RNA and Cytosolic DNA, but Not to Interferon-α Stimulation, in TRIM56-Deficient Cells.2
360848502022TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity.6
362091172022Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1.19
364713472022TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein.8
350622932022Impaired Antiviral Responses to Extracellular Double-Stranded RNA and Cytosolic DNA, but Not to Interferon-α Stimulation, in TRIM56-Deficient Cells.2
360848502022TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity.6
362091172022Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1.19
364713472022TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein.8
335770262021TRIM56 suppresses the malignant development of hepatocellular carcinoma via targeting RBM24 and inactivating the Wnt signaling.7

Citation

Dessen P

TRIM56 (tripartite motif containing 56)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57264/trim56-(tripartite-motif-containing-56)