RPL35A (ribosomal protein L35a)

2018-02-01  

Identity

HGNC
LOCATION
3q29
LOCUSID
ALIAS
DBA5,L35A,eL33
FUSION GENES

Other Information

Locus ID:

NCBI: 6165
MIM: 180468
HGNC: 10345
Ensembl: ENSG00000182899

Variants:

dbSNP: 6165
ClinVar: 6165
TCGA: ENSG00000182899
COSMIC: RPL35A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182899ENST00000429437F8WBS5
ENSG00000182899ENST00000439255F8WB72
ENSG00000182899ENST00000442341C9K025
ENSG00000182899ENST00000448864P18077
ENSG00000182899ENST00000647248P18077

Expression (GTEx)

0
500
1000
1500

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Ribosome, eukaryotesKEGGhsa_M00177
Ribosome, eukaryotesKEGGM00177
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
Eukaryotic Translation InitiationREACTOMER-HSA-72613
Cap-dependent Translation InitiationREACTOMER-HSA-72737
Formation of a pool of free 40S subunitsREACTOMER-HSA-72689
GTP hydrolysis and joining of the 60S ribosomal subunitREACTOMER-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expressionREACTOMER-HSA-156827
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Eukaryotic Translation ElongationREACTOMER-HSA-156842
Peptide chain elongationREACTOMER-HSA-156902
Eukaryotic Translation TerminationREACTOMER-HSA-72764
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
Influenza InfectionREACTOMER-HSA-168254
Influenza Life CycleREACTOMER-HSA-168255
Influenza Viral RNA Transcription and ReplicationREACTOMER-HSA-168273
Viral mRNA TranslationREACTOMER-HSA-192823
Gene ExpressionREACTOMER-HSA-74160
Nonsense-Mediated Decay (NMD)REACTOMER-HSA-927802
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)REACTOMER-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)REACTOMER-HSA-975956
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Selenoamino acid metabolismREACTOMER-HSA-2408522
Selenocysteine synthesisREACTOMER-HSA-2408557
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

References

Pubmed IDYearTitleCitations
383959082024RPL35A promotes the progression of cholangiocarcinoma by mediating HSPA8 ubiquitination.0
384365442024RPL35A drives ovarian cancer progression by promoting the binding of YY1 to CTCF promoter.0
383959082024RPL35A promotes the progression of cholangiocarcinoma by mediating HSPA8 ubiquitination.0
384365442024RPL35A drives ovarian cancer progression by promoting the binding of YY1 to CTCF promoter.0
322418392021Genotype-phenotype association and variant characterization in Diamond-Blackfan anemia caused by pathogenic variants in RPL35A.10
322418392021Genotype-phenotype association and variant characterization in Diamond-Blackfan anemia caused by pathogenic variants in RPL35A.10
284327402017Novel 3q27.2-qter deletion in a patient with Diamond-Blackfan anemia and immunodeficiency: Case report and review of literature.3
284327402017Novel 3q27.2-qter deletion in a patient with Diamond-Blackfan anemia and immunodeficiency: Case report and review of literature.3
222627662012Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia.24
222627662012Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia.24
220459822011Ribosomal protein gene deletions in Diamond-Blackfan anemia.74
220459822011Ribosomal protein gene deletions in Diamond-Blackfan anemia.74
197732622010Diamond-Blackfan anemia: genotype-phenotype correlations in Italian patients with RPL5 and RPL11 mutations.40
203785602010Mutations in the ribosomal protein genes in Japanese patients with Diamond-Blackfan anemia.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20

Citation

Dessen P

RPL35A (ribosomal protein L35a)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57270/rpl35a-(ribosomal-protein-l35a)