Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27005
MIM: 604729
HGNC: 12620
Ensembl: ENSG00000143258
Variants:
dbSNP: 27005
ClinVar: 27005
TCGA: ENSG00000143258
COSMIC: USP21
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37964466 | 2024 | Inhibition of USP21 leads to ovarian carcinoma cell death by suppressing MAPK signaling. | 0 |
| 37964466 | 2024 | Inhibition of USP21 leads to ovarian carcinoma cell death by suppressing MAPK signaling. | 0 |
| 36285444 | 2023 | Salt-like transcription factor 4 promotes laryngeal cancer progression through transcriptional activation of ubiquitin-specific protease 21 to stabilize Yin Yang 1. | 0 |
| 37434557 | 2023 | c-JUN-induced upregulation of LINC00174 contributes to colorectal cancer proliferation and invasion through accelerating USP21 expression. | 2 |
| 36285444 | 2023 | Salt-like transcription factor 4 promotes laryngeal cancer progression through transcriptional activation of ubiquitin-specific protease 21 to stabilize Yin Yang 1. | 0 |
| 37434557 | 2023 | c-JUN-induced upregulation of LINC00174 contributes to colorectal cancer proliferation and invasion through accelerating USP21 expression. | 2 |
| 34825342 | 2022 | USP21 regulates Hippo signaling to promote radioresistance by deubiquitinating FOXM1 in cervical cancer. | 10 |
| 35974001 | 2022 | USP21 promotes self-renewal and tumorigenicity of mesenchymal glioblastoma stem cells by deubiquitinating and stabilizing FOXD1. | 9 |
| 36095935 | 2022 | USP21 accelerates the proliferation and glycolysis of esophageal cancer cells by regulating the STAT3/FOXO1 pathway. | 3 |
| 34825342 | 2022 | USP21 regulates Hippo signaling to promote radioresistance by deubiquitinating FOXM1 in cervical cancer. | 10 |
| 35974001 | 2022 | USP21 promotes self-renewal and tumorigenicity of mesenchymal glioblastoma stem cells by deubiquitinating and stabilizing FOXD1. | 9 |
| 36095935 | 2022 | USP21 accelerates the proliferation and glycolysis of esophageal cancer cells by regulating the STAT3/FOXO1 pathway. | 3 |
| 33052017 | 2021 | USP21 upregulation in cholangiocarcinoma promotes cell proliferation and migration in a deubiquitinase-dependent manner. | 7 |
| 33389794 | 2021 | USP21 promotes cell proliferation by maintaining the EZH2 level in diffuse large B-cell lymphoma. | 6 |
| 33582217 | 2021 | Disulfiram and 6-Thioguanine synergistically inhibit the enzymatic activities of USP2 and USP21. | 8 |
Citation
Dessen P
USP21 (ubiquitin specific peptidase 21)
Atlas Genet Cytogenet Oncol Haematol. 2018-02-01
Online version: http://atlasgeneticsoncology.org/gene/57285/usp21-(ubiquitin-specific-peptidase-21)
