GBP3 (guanylate binding protein 3)

2018-02-01  

Identity

HGNC
LOCATION
1p22.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 2635
MIM: 600413
HGNC: 4184
Ensembl: ENSG00000117226

Variants:

dbSNP: 2635
ClinVar: 2635
TCGA: ENSG00000117226
COSMIC: GBP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117226ENST00000235878F6SPX6
ENSG00000117226ENST00000370481Q9H0R5
ENSG00000117226ENST00000445969Q5T8M0
ENSG00000117226ENST00000461384H3BNS1
ENSG00000117226ENST00000489444F6X827
ENSG00000117226ENST00000493594H3BRX6
ENSG00000117226ENST00000564665H3BPH2
ENSG00000117226ENST00000568006H3BP53

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
NOD-like receptor signaling pathwayKEGGko04621
NOD-like receptor signaling pathwayKEGGhsa04621
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371612542023The function of guanylate binding protein 3 (GBP3) in human cancers by pan-cancer bioinformatics.0
371612542023The function of guanylate binding protein 3 (GBP3) in human cancers by pan-cancer bioinformatics.0
357801812022GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.6
357801812022GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.6
291283632018GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.16
291283632018GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.16
221063662012A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication.58
221063662012A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication.58
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37

Citation

Dessen P

GBP3 (guanylate binding protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57287/gbp3-(guanylate-binding-protein-3)