MYO1E (myosin IE)

2018-02-01  

Identity

HGNC
LOCATION
15q22.2
LOCUSID
ALIAS
FSGS6,HuncM-IC,MYO1C
FUSION GENES

Other Information

Locus ID:

NCBI: 4643
MIM: 601479
HGNC: 7599
Ensembl: ENSG00000157483

Variants:

dbSNP: 4643
ClinVar: 4643
TCGA: ENSG00000157483
COSMIC: MYO1E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000157483ENST00000288235Q12965
ENSG00000157483ENST00000288235Q4KMR3
ENSG00000157483ENST00000558571H0YN00
ENSG00000157483ENST00000559269H0YLJ4
ENSG00000157483ENST00000559412H0YNB0
ENSG00000157483ENST00000559489H0YLE5
ENSG00000157483ENST00000560749H0YNQ8

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
357237362023Focal segmental glomerulosclerosis and proteinuria associated with Myo1E mutations: novel variants and histological phenotype analysis.1
369147202023Myo1e overexpression in lung adenocarcinoma is associated with increased risk of mortality.0
357237362023Focal segmental glomerulosclerosis and proteinuria associated with Myo1E mutations: novel variants and histological phenotype analysis.1
369147202023Myo1e overexpression in lung adenocarcinoma is associated with increased risk of mortality.0
363160952022Steroid-Resistant Nephrotic Syndrome-Associated MYO1E Mutations Have Differential Effects on Myosin 1e Localization, Dynamics, and Activity.2
363160952022Steroid-Resistant Nephrotic Syndrome-Associated MYO1E Mutations Have Differential Effects on Myosin 1e Localization, Dynamics, and Activity.2
306016982019Tail domains of myosin-1e regulate phosphatidylinositol signaling and F-actin polymerization at the ventral layer of podosomes.10
306016982019Tail domains of myosin-1e regulate phosphatidylinositol signaling and F-actin polymerization at the ventral layer of podosomes.10
273298402016Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation.24
275024872016ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips.17
273298402016Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation.24
275024872016ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips.17
257393412015Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease.22
257393412015Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease.22
247508282014[Mutational analysis of MYO1E in Chinese children with familial steroid-resistant nephrotic syndrome].0

Citation

Dessen P

MYO1E (myosin IE)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57299/myo1e-(myosin-ie)