ATP5PB (ATP synthase peripheral stalk-membrane subunit b)

2018-02-01  

Identity

HGNC
ATP5PB
LOCATION
1p13.2
LOCUSID
515
ALIAS
ATP5F1,PIG47

Other Information

Locus ID:

NCBI: 515
MIM: 603270
HGNC: 840
Ensembl: ENSG00000116459

Variants:

dbSNP: 515
ClinVar: 515
TCGA: ENSG00000116459
COSMIC: ATP5PB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116459ENST00000369722P24539
ENSG00000116459ENST00000369722Q08ET0
ENSG00000116459ENST00000483994Q5QNZ2

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
Alzheimer's diseaseKEGGko05010
Huntington's diseaseKEGGko05016
Oxidative phosphorylationKEGGhsa00190
Alzheimer's diseaseKEGGhsa05010
Parkinson's diseaseKEGGhsa05012
Huntington's diseaseKEGGhsa05016
Metabolic pathwaysKEGGhsa01100
F-type ATPase, eukaryotesKEGGhsa_M00158
F-type ATPase, eukaryotesKEGGM00158
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Formation of ATP by chemiosmotic couplingREACTOMER-HSA-163210

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
200385172010Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance.0
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
200385172010Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance.0
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
196507682009Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits FoF1-ATPase activity loss.18
198345352009Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.29
196507682009Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits FoF1-ATPase activity loss.18
198345352009Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.29
190645712008Polymorphisms in mitochondrial genes and prostate cancer risk.22
190645712008Polymorphisms in mitochondrial genes and prostate cancer risk.22

Citation

Dessen P

ATP5PB (ATP synthase peripheral stalk-membrane subunit b)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57321/atp5pb-(atp-synthase-peripheral-stalk-membrane-subunit-b)