TAS1R1 (taste 1 receptor member 1)

2018-02-01  

Identity

HGNC
LOCATION
1p36.31
LOCUSID
ALIAS
GM148,GPR70,T1R1,TR1
FUSION GENES

Other Information

Locus ID:

NCBI: 80835
MIM: 606225
HGNC: 14448
Ensembl: ENSG00000173662

Variants:

dbSNP: 80835
ClinVar: 80835
TCGA: ENSG00000173662
COSMIC: TAS1R1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173662ENST00000333172Q7RTX1
ENSG00000173662ENST00000351136Q7RTX1
ENSG00000173662ENST00000411823H7C3W7
ENSG00000173662ENST00000415267H0Y6X0

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Pathways

PathwaySourceExternal ID
Taste transductionKEGGko04742
Taste transductionKEGGhsa04742
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class C/3 (Metabotropic glutamate/pheromone receptors)REACTOMER-HSA-420499

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
375397672023Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease.0
375397672023Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease.0
336541872021Polymorphic variants in Sweet and Umami taste receptor genes and birthweight.2
336541872021Polymorphic variants in Sweet and Umami taste receptor genes and birthweight.2
321382142020Oral Microbiota Profile Associates with Sugar Intake and Taste Preference Genes.25
325787982020Association of taste receptor gene polymorphisms with dental caries.3
321382142020Oral Microbiota Profile Associates with Sugar Intake and Taste Preference Genes.25
325787982020Association of taste receptor gene polymorphisms with dental caries.3
310923292019Understanding the molecular mechanism of umami recognition by T1R1-T1R3 using molecular dynamics simulations.6
310923292019Understanding the molecular mechanism of umami recognition by T1R1-T1R3 using molecular dynamics simulations.6
305180432018TAS1R1 and TAS1R3 Polymorphisms Relate to Energy and Protein-Rich Food Choices from a Buffet Meal Respectively.3
305180432018TAS1R1 and TAS1R3 Polymorphisms Relate to Energy and Protein-Rich Food Choices from a Buffet Meal Respectively.3
273218752016Variations in TAS1R taste receptor gene family modify food intake and gastric cancer risk in a Korean population.10
273218752016Variations in TAS1R taste receptor gene family modify food intake and gastric cancer risk in a Korean population.10
240002322013Do polymorphisms in the TAS1R1 gene contribute to broader differences in human taste intensity?12

Citation

Dessen P

TAS1R1 (taste 1 receptor member 1)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57322/tas1r1-(taste-1-receptor-member-1)