SLC4A11 (solute carrier family 4 member 11)

2018-02-01  

Identity

HGNC
LOCATION
20p13
LOCUSID
ALIAS
BTR1,CDPD1,CHED,CHED2,NABC1,dJ794I6.2

Other Information

Locus ID:

NCBI: 83959
MIM: 610206
HGNC: 16438
Ensembl: ENSG00000088836

Variants:

dbSNP: 83959
ClinVar: 83959
TCGA: ENSG00000088836
COSMIC: SLC4A11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000088836ENST00000380056Q8NBS3
ENSG00000088836ENST00000380059Q8NBS3
ENSG00000088836ENST00000437836V9GXZ2
ENSG00000088836ENST00000474451V9GYK6
ENSG00000088836ENST00000642402Q8NBS3
ENSG00000088836ENST00000644011A0A2R8Y7S1
ENSG00000088836ENST00000644692A0A2R8Y4A6
ENSG00000088836ENST00000644862A0A2R8YEG3
ENSG00000088836ENST00000645524A0A2R8Y6X5
ENSG00000088836ENST00000647296A0A2R8YFD9

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382526452024Investigation of the functional impact of CHED- and FECD4-associated SLC4A11 mutations in human corneal endothelial cells.0
382526452024Investigation of the functional impact of CHED- and FECD4-associated SLC4A11 mutations in human corneal endothelial cells.0
377879912023Pathogenicity and Function Analysis of Two Novel SLC4A11 Variants in Patients With Congenital Hereditary Endothelial Dystrophy.0
377889932023Structural insights into the conformational changes of BTR1/SLC4A11 in complex with PIP(2).5
377879912023Pathogenicity and Function Analysis of Two Novel SLC4A11 Variants in Patients With Congenital Hereditary Endothelial Dystrophy.0
377889932023Structural insights into the conformational changes of BTR1/SLC4A11 in complex with PIP(2).5
338794712022Autosomal recessive congenital hereditary corneal dystrophy associated with a novel SLC4A11 mutation in two consanguineous Tunisian families.2
352919252022Compound heterozygous mutations in the SLC4A11 gene associated with congenital hereditary endothelial dystrophy in a Chinese family.1
359935142022Corneal dystrophy mutations R125H and R804H disable SLC4A11 by altering the extracellular pH dependence of the intracellular pK that governs H(+)(OH(-)) transport.0
360371972022Mutational analysis in sodium-borate cotransporter SLC4A11 in consanguineous families from Punjab, Pakistan.4
361159912022Identification and in silico analysis of a spectrum of SLC4A11 variations in Indian familial and sporadic cases of congenital hereditary endothelial dystrophy.4
338794712022Autosomal recessive congenital hereditary corneal dystrophy associated with a novel SLC4A11 mutation in two consanguineous Tunisian families.2
352919252022Compound heterozygous mutations in the SLC4A11 gene associated with congenital hereditary endothelial dystrophy in a Chinese family.1
359935142022Corneal dystrophy mutations R125H and R804H disable SLC4A11 by altering the extracellular pH dependence of the intracellular pK that governs H(+)(OH(-)) transport.0
360371972022Mutational analysis in sodium-borate cotransporter SLC4A11 in consanguineous families from Punjab, Pakistan.4

Citation

Dessen P

SLC4A11 (solute carrier family 4 member 11)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57323/slc4a11-(solute-carrier-family-4-member-11)