Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84893
MIM: 607222
HGNC: 13620
Ensembl: ENSG00000134452
Variants:
dbSNP: 84893
ClinVar: 84893
TCGA: ENSG00000134452
COSMIC: FBH1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000134452 | ENST00000362091 | Q8NFZ0 |
| ENSG00000134452 | ENST00000379999 | Q8NFZ0 |
| ENSG00000134452 | ENST00000397269 | F6UZG9 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38103522 | 2024 | FBH1 deficiency sensitizes cells to WEE1 inhibition by promoting mitotic catastrophe. | 0 |
| 38103522 | 2024 | FBH1 deficiency sensitizes cells to WEE1 inhibition by promoting mitotic catastrophe. | 0 |
| 36990095 | 2023 | Molecular insight into the PCNA-binding mode of FBH1. | 2 |
| 36990095 | 2023 | Molecular insight into the PCNA-binding mode of FBH1. | 2 |
| 29467415 | 2018 | PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation. | 107 |
| 29467415 | 2018 | PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation. | 107 |
| 28317220 | 2017 | Rare FBXO18 variations and risk of schizophrenia: Whole-exome sequencing in two parent-affected offspring trios followed by resequencing and case-control studies. | 1 |
| 28317220 | 2017 | Rare FBXO18 variations and risk of schizophrenia: Whole-exome sequencing in two parent-affected offspring trios followed by resequencing and case-control studies. | 1 |
| 25585578 | 2015 | FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51. | 35 |
| 25585578 | 2015 | FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51. | 35 |
| 23319600 | 2013 | FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress. | 33 |
| 23361013 | 2013 | FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress. | 53 |
| 23393192 | 2013 | Single-molecule sorting reveals how ubiquitylation affects substrate recognition and activities of FBH1 helicase. | 20 |
| 23466708 | 2013 | FBH1 protects melanocytes from transformation and is deregulated in melanomas. | 12 |
| 23677613 | 2013 | The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells. | 45 |
Citation
Dessen P
FBH1 (F-box DNA helicase 1)
Atlas Genet Cytogenet Oncol Haematol. 2018-02-01
Online version: http://atlasgeneticsoncology.org/gene/57326/fbh1-(f-box-dna-helicase-1)
