TBXT (T-box transcription factor T)

2018-02-01  

Identity

HGNC
TBXT
LOCATION
6q27
LOCUSID
6862
ALIAS
SAVA,T,TFT

Other Information

Locus ID:

NCBI: 6862
MIM: 601397
HGNC: 11515
Ensembl: ENSG00000164458

Variants:

dbSNP: 6862
ClinVar: 6862
TCGA: ENSG00000164458
COSMIC: TBXT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164458ENST00000296946O15178
ENSG00000164458ENST00000366871O15178
ENSG00000164458ENST00000366876J3KP65
ENSG00000164458ENST00000461348H0YM91

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
384189172024On the genetic basis of tail-loss evolution in humans and apes.0
384189172024On the genetic basis of tail-loss evolution in humans and apes.0
348377142022Association between TBXT rs2305089 polymorphism and chordoma in Iranian patients identified by a developed T-ARMS-PCR assay.3
348377142022Association between TBXT rs2305089 polymorphism and chordoma in Iranian patients identified by a developed T-ARMS-PCR assay.3
326728672021Genetic variants of TBX6 and TBXT identified in patients with congenital scoliosis in Southern China.6
335217022021Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity.11
337343192021Machine learning based tissue analysis reveals Brachyury has a diagnosis value in breast cancer.2
343394872021miR-219-5p targets TBXT and inhibits breast cancer cell EMT and cell migration and invasion.3
343925822021Recurrent loss of chromosome 22 and SMARCB1 deletion in extra-axial chordoma: A clinicopathological and molecular analysis.5
326728672021Genetic variants of TBX6 and TBXT identified in patients with congenital scoliosis in Southern China.6
335217022021Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity.11
337343192021Machine learning based tissue analysis reveals Brachyury has a diagnosis value in breast cancer.2
343394872021miR-219-5p targets TBXT and inhibits breast cancer cell EMT and cell migration and invasion.3
343925822021Recurrent loss of chromosome 22 and SMARCB1 deletion in extra-axial chordoma: A clinicopathological and molecular analysis.5
327858472020Brachyury Is Associated with Glioma Differentiation and Response to Temozolomide.3

Citation

Dessen P

TBXT (T-box transcription factor T)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57327/tbxt-(t-box-transcription-factor-t)