Identity
HGNC
LOCATION
3q13.2
LOCUSID
ALIAS
APG3,APG3-LIKE,APG3L,PC3-96
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64422
MIM: 609606
HGNC: 20962
Ensembl: ENSG00000144848
Variants:
dbSNP: 64422
ClinVar: 64422
TCGA: ENSG00000144848
COSMIC: ATG3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000144848 | ENST00000283290 | Q9NT62 |
| ENSG00000144848 | ENST00000402314 | Q9NT62 |
| ENSG00000144848 | ENST00000492886 | C9JNW8 |
| ENSG00000144848 | ENST00000496423 | F8WDI0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34555423 | 2022 | Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function. | 13 |
| 34555423 | 2022 | Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function. | 13 |
| 33382073 | 2021 | Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3. | 5 |
| 33446636 | 2021 | An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy. | 17 |
| 33382073 | 2021 | Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3. | 5 |
| 33446636 | 2021 | An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy. | 17 |
| 31549407 | 2020 | LncRNA NEAT1 promotes autophagy via regulating miR-204/ATG3 and enhanced cell resistance to sorafenib in hepatocellular carcinoma. | 56 |
| 32258130 | 2020 | Let-7c-3p Regulates Autophagy under Oxidative Stress by Targeting ATG3 in Lens Epithelial Cells. | 11 |
| 31549407 | 2020 | LncRNA NEAT1 promotes autophagy via regulating miR-204/ATG3 and enhanced cell resistance to sorafenib in hepatocellular carcinoma. | 56 |
| 32258130 | 2020 | Let-7c-3p Regulates Autophagy under Oxidative Stress by Targeting ATG3 in Lens Epithelial Cells. | 11 |
| 30794914 | 2019 | Long non-coding RNA PVT1 promotes autophagy as ceRNA to target ATG3 by sponging microRNA-365 in hepatocellular carcinoma. | 39 |
| 30794914 | 2019 | Long non-coding RNA PVT1 promotes autophagy as ceRNA to target ATG3 by sponging microRNA-365 in hepatocellular carcinoma. | 39 |
| 29138833 | 2018 | miR-16 mimics inhibit TGF-β1-induced epithelial-to-mesenchymal transition via activation of autophagy in non-small cell lung carcinoma cells. | 18 |
| 29300789 | 2018 | Mycobacterium tuberculosis-induced miR-155 subverts autophagy by targeting ATG3 in human dendritic cells. | 53 |
| 29712776 | 2018 | eIF5A is required for autophagy by mediating ATG3 translation. | 42 |
Citation
Dessen P
ATG3 (autophagy related 3)
Atlas Genet Cytogenet Oncol Haematol. 2018-02-01
Online version: http://atlasgeneticsoncology.org/gene/57331/atg3-(autophagy-related-3)
