APELA (apelin receptor early endogenous ligand)

2018-02-01  

Identity

HGNC
LOCATION
4q32.3
LOCUSID
ALIAS
ELA,Ende,tdl

Other Information

Locus ID:

NCBI: 100506013
MIM: 615594
HGNC: 48925
Ensembl: ENSG00000248329

Variants:

dbSNP: 100506013
ClinVar: 100506013
TCGA: ENSG00000248329
COSMIC: APELA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000248329ENST00000507152P0DMC3
ENSG00000248329ENST00000507152X5D2P3
ENSG00000248329ENST00000510062P0DMC3
ENSG00000248329ENST00000510062X5D2P3
ENSG00000248329ENST00000515275P0DMC3
ENSG00000248329ENST00000515275X5D2P3

Expression (GTEx)

0
1
2
3
4

References

Pubmed IDYearTitleCitations
290365642017Elabela-APJ axis: a novel therapy target for cardiovascular diseases.2
300707012018Targeting drugs to APJ receptor: From signaling to pathophysiological effects.1
281379362017Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension.0
283718222017ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage.0
290790362017APELA promotes tumour growth and cell migration in ovarian cancer in a p53-dependent manner.0
296946632018A Novel Candidate Molecule in the Pathological Grading of Gliomas: ELABELA.0
300489932018Serum Elabela/Toddler Levels Are Associated with Albuminuria in Patients with Type 2 Diabetes.0
302677322018Elabela, a newly discovered APJ ligand: Similarities and differences with Apelin.0
305766652019ELABELA concentration is not decreased in maternal plasma before the onset of preeclampsia.0
307197412019Variants in the 5'-UTR of APELA gene in women with preeclampsia.0

Citation

Dessen P

APELA (apelin receptor early endogenous ligand)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57333/apela-(apelin-receptor-early-endogenous-ligand)