Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1071
MIM: 118470
HGNC: 1869
Ensembl: ENSG00000087237
Variants:
dbSNP: 1071
ClinVar: 1071
TCGA: ENSG00000087237
COSMIC: CETP
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA133950441 | hmg coa reductase inhibitors | Chemical | ClinicalAnnotation | associated | PD | 14660992, 20195290 | |
| PA443796 | Coronary Artery Disease | Disease | ClinicalAnnotation | associated | PD | 14660992, 15044381, 15856070, 18957472, 9420339 | |
| PA444516 | Hypercholesterolemia | Disease | ClinicalAnnotation | associated | PD | 15856070, 16002074, 17931083 | |
| PA444517 | Hyperlipoproteinemia Type II | Disease | ClinicalAnnotation | associated | PD | 15856070, 17931083 | |
| PA444528 | Hyperlipidemias | Disease | ClinicalAnnotation | associated | PD | 20195290 | |
| PA448500 | atorvastatin | Chemical | ClinicalAnnotation | associated | PD | 12663600, 15856070, 16103896 | |
| PA449688 | fluvastatin | Chemical | ClinicalAnnotation | associated | PD | 16002074 | |
| PA450272 | lovastatin | Chemical | ClinicalAnnotation | associated | PD | 16103896 | |
| PA451089 | pravastatin | Chemical | ClinicalAnnotation | associated | PD | 14660992, 15044381, 15856070, 18957472, 9420339 | |
| PA451363 | simvastatin | Chemical | ClinicalAnnotation | associated | PD | 15856070, 17931083 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38265339 | 2024 | CETP gene polymorphisms and haplotypes are explanatory variables for HDL cholesterol level in sickle cell disease. | 1 |
| 38265339 | 2024 | CETP gene polymorphisms and haplotypes are explanatory variables for HDL cholesterol level in sickle cell disease. | 1 |
| 36318507 | 2023 | Elevated Serum Low-Density Lipoproteins-Cholesterol Levels and B1B2/B2B2 CETP Genotype Are Positively Associated with Nonalcoholic Fatty Liver Disease in Women with Gallstone Disease. | 1 |
| 36652934 | 2023 | Abdominal Obesity, Excessive Adiposity, and the Taq1B CETP Variant Are Positively Associated with Serum Lipid Levels in Mexican Women. | 1 |
| 36881278 | 2023 | Structure-based mechanism and inhibition of cholesteryl ester transfer protein. | 7 |
| 37054880 | 2023 | Adcy9 Gene Inactivation Improves Cardiac Function After Myocardial Infarction in Mice. | 0 |
| 37250494 | 2023 | A Polynesian-specific missense CETP variant alters the lipid profile. | 0 |
| 37373432 | 2023 | Association of CETP Gene Polymorphisms and Haplotypes with Cardiovascular Risk. | 1 |
| 37407953 | 2023 | Dietary acid load and its interaction with CETP TaqB1 polymorphisms on lipid profile among patients with Type 2 diabetes mellitus. | 0 |
| 37446094 | 2023 | Association of Common Variants of APOE, CETP, and the 9p21.3 Chromosomal Region with the Risk of Myocardial Infarction: A Prospective Study. | 3 |
| 37639752 | 2023 | Structural insights on the deformations induced by various mutations on cholesteryl ester transfer protein. | 1 |
| 37833739 | 2023 | Association between HMGCR, CRP, and CETP gene polymorphisms and metabolic/inflammatory serum profile in healthy adolescents. | 1 |
| 37929782 | 2023 | Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the CETP Gene. | 0 |
| 38039300 | 2023 | Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP. | 0 |
| 38057013 | 2023 | Association of dyslipidemia with single nucleotide polymorphisms of the cholesteryl ester transfer protein gene and cardiovascular disease risk factors in a highly admixed population. | 1 |
Citation
Dessen P
CETP (cholesteryl ester transfer protein)
Atlas Genet Cytogenet Oncol Haematol. 2018-02-01
Online version: http://atlasgeneticsoncology.org/gene/57338/cetp-(cholesteryl-ester-transfer-protein)
