Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2747
MIM: 300144
HGNC: 4336
Ensembl: ENSG00000182890
Variants:
dbSNP: 2747
ClinVar: 2747
TCGA: ENSG00000182890
COSMIC: GLUD2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000182890 | ENST00000328078 | P49448 |
| ENSG00000182890 | ENST00000328078 | A0A140VK14 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 39052831 | 2024 | Lack of evidence for direct ligand-gated ion channel activity of GluD receptors. | 0 |
| 39052831 | 2024 | Lack of evidence for direct ligand-gated ion channel activity of GluD receptors. | 0 |
| 33421122 | 2021 | Crystal structure of glutamate dehydrogenase 2, a positively selected novel human enzyme involved in brain biology and cancer pathophysiology. | 6 |
| 33421122 | 2021 | Crystal structure of glutamate dehydrogenase 2, a positively selected novel human enzyme involved in brain biology and cancer pathophysiology. | 6 |
| 32917661 | 2020 | Ammonia inhibits energy metabolism in astrocytes in a rapid and glutamate dehydrogenase 2-dependent manner. | 13 |
| 33093440 | 2020 | Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease. | 7 |
| 32917661 | 2020 | Ammonia inhibits energy metabolism in astrocytes in a rapid and glutamate dehydrogenase 2-dependent manner. | 13 |
| 33093440 | 2020 | Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease. | 7 |
| 29943084 | 2019 | Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes. | 7 |
| 31400387 | 2019 | Transgenic expression of the positive selected human GLUD2 gene improves in vivo glucose homeostasis by regulating basic insulin secretion. | 3 |
| 29943084 | 2019 | Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes. | 7 |
| 31400387 | 2019 | Transgenic expression of the positive selected human GLUD2 gene improves in vivo glucose homeostasis by regulating basic insulin secretion. | 3 |
| 29146184 | 2018 | Glutamate production from ammonia via glutamate dehydrogenase 2 activity supports cancer cell proliferation under glutamine depletion. | 19 |
| 30045961 | 2018 | Glutamate receptor δ2 serum antibodies in pediatric opsoclonus myoclonus ataxia syndrome. | 14 |
| 30314897 | 2018 | Mitochondrial enzyme GLUD2 plays a critical role in glioblastoma progression. | 16 |
Citation
Dessen P
GLUD2 (glutamate dehydrogenase 2)
Atlas Genet Cytogenet Oncol Haematol. 2018-02-01
Online version: http://atlasgeneticsoncology.org/gene/57341/glud2-(glutamate-dehydrogenase-2)
