Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79037
MIM: 617012
HGNC: 32190
Ensembl: ENSG00000213413
Variants:
dbSNP: 79037
ClinVar: 79037
TCGA: ENSG00000213413
COSMIC: PVRIG
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000213413 | ENST00000317271 | Q6DKI7 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36788088 | 2023 | Nonredundant Upregulation of CD112R (PVRIG) and PD-1 on Cytotoxic T Lymphocytes Located in T Cell Nests of Colorectal Cancer. | 1 |
| 36788088 | 2023 | Nonredundant Upregulation of CD112R (PVRIG) and PD-1 on Cytotoxic T Lymphocytes Located in T Cell Nests of Colorectal Cancer. | 1 |
| 33147937 | 2021 | PVRIG is a novel natural killer cell immune checkpoint receptor in acute myeloid leukemia. | 11 |
| 33298247 | 2021 | Hitting the complexity of the TIGIT-CD96-CD112R-CD226 axis for next-generation cancer immunotherapy. | 25 |
| 33903974 | 2021 | COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade. | 11 |
| 33147937 | 2021 | PVRIG is a novel natural killer cell immune checkpoint receptor in acute myeloid leukemia. | 11 |
| 33298247 | 2021 | Hitting the complexity of the TIGIT-CD96-CD112R-CD226 axis for next-generation cancer immunotherapy. | 25 |
| 33903974 | 2021 | COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade. | 11 |
| 30659054 | 2019 | PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8(+) T-cell Function. | 84 |
| 30659054 | 2019 | PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8(+) T-cell Function. | 84 |
| 28623459 | 2017 | Blockade of CD112R and TIGIT signaling sensitizes human natural killer cell functions. | 84 |
| 28623459 | 2017 | Blockade of CD112R and TIGIT signaling sensitizes human natural killer cell functions. | 84 |
| 26755705 | 2016 | Identification of CD112R as a novel checkpoint for human T cells. | 111 |
| 26755705 | 2016 | Identification of CD112R as a novel checkpoint for human T cells. | 111 |
Citation
Dessen P
PVRIG (PVR related immunoglobulin domain containing)
Atlas Genet Cytogenet Oncol Haematol. 2018-02-01
Online version: http://atlasgeneticsoncology.org/gene/57344/gene-explorer/deep-insight-explorer/
