TSPAN5 (tetraspanin 5)

2018-02-01  

Identity

HGNC
LOCATION
4q23
LOCUSID
ALIAS
NET-4,NET4,TM4SF9,TSPAN-5
FUSION GENES

Other Information

Locus ID:

NCBI: 10098
MIM: 613136
HGNC: 17753
Ensembl: ENSG00000168785

Variants:

dbSNP: 10098
ClinVar: 10098
TCGA: ENSG00000168785
COSMIC: TSPAN5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168785ENST00000305798P62079
ENSG00000168785ENST00000505184B7Z317
ENSG00000168785ENST00000508798D6RAR1
ENSG00000168785ENST00000511651D6RGZ7
ENSG00000168785ENST00000511800D6RBT5
ENSG00000168785ENST00000515287D6R9N6
ENSG00000168785ENST00000515440H0Y8W4

Expression (GTEx)

0
50
100
150
200

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA10074escitalopramChemicalClinicalAnnotationassociatedPD26903268
PA447207Depressive DisorderDiseaseClinicalAnnotationassociatedPD26903268
PA449015citalopramChemicalClinicalAnnotationassociatedPD26903268

References

Pubmed IDYearTitleCitations
384228042024The relationship between expression of Tspan5 mRNA in maternal-fetal interface and tubal pregnancy.0
384228042024The relationship between expression of Tspan5 mRNA in maternal-fetal interface and tubal pregnancy.0
327536862021TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response.14
339551492021Tspan5 promotes epithelial-mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling.13
327536862021TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response.14
339551492021Tspan5 promotes epithelial-mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling.13
320962992020miR-155 increases stemness and decitabine resistance in triple-negative breast cancer cells by inhibiting TSPAN5.17
320962992020miR-155 increases stemness and decitabine resistance in triple-negative breast cancer cells by inhibiting TSPAN5.17
316656292019TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering.11
316656292019TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering.11
299083762018The increased level of Tspan5 in villi suggests more proliferation and invasiveness of trophoblasts in tubal pregnancy.1
299083762018The increased level of Tspan5 in villi suggests more proliferation and invasiveness of trophoblasts in tubal pregnancy.1
284282482017New insights into the tetraspanin Tspan5 using novel monoclonal antibodies.21
286002922017ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration.29
284282482017New insights into the tetraspanin Tspan5 using novel monoclonal antibodies.21

Citation

Dessen P

TSPAN5 (tetraspanin 5)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57347/tspan5-(tetraspanin-5)