Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9669
MIM: 606086
HGNC: 30793
Ensembl: ENSG00000158417
Variants:
dbSNP: 9669
ClinVar: 9669
TCGA: ENSG00000158417
COSMIC: EIF5B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000158417 | ENST00000289371 | O60841 |
| ENSG00000158417 | ENST00000617677 | A0A087WUT6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34923394 | 2022 | Dynamic interaction network involving the conserved intrinsically disordered regions in human eIF5. | 2 |
| 35732735 | 2022 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. | 19 |
| 34923394 | 2022 | Dynamic interaction network involving the conserved intrinsically disordered regions in human eIF5. | 2 |
| 35732735 | 2022 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. | 19 |
| 33123915 | 2021 | Depletion of eukaryotic initiation factor 5B (eIF5B) reprograms the cellular transcriptome and leads to activation of endoplasmic reticulum (ER) stress and c-Jun N-terminal kinase (JNK). | 4 |
| 34525951 | 2021 | eIF5B regulates the expression of PD-L1 in prostate cancer cells by interacting with Wig1. | 3 |
| 33123915 | 2021 | Depletion of eukaryotic initiation factor 5B (eIF5B) reprograms the cellular transcriptome and leads to activation of endoplasmic reticulum (ER) stress and c-Jun N-terminal kinase (JNK). | 4 |
| 34525951 | 2021 | eIF5B regulates the expression of PD-L1 in prostate cancer cells by interacting with Wig1. | 3 |
| 31671279 | 2020 | Eukaryotic initiation factor 5B (eIF5B) regulates temozolomide-mediated apoptosis in brain tumour stem cells (BTSCs). | 3 |
| 32984844 | 2020 | eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer. | 46 |
| 31671279 | 2020 | Eukaryotic initiation factor 5B (eIF5B) regulates temozolomide-mediated apoptosis in brain tumour stem cells (BTSCs). | 3 |
| 32984844 | 2020 | eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer. | 46 |
| 30670698 | 2019 | Eukaryotic initiation factor 5B (eIF5B) provides a critical cell survival switch to glioblastoma cells via regulation of apoptosis. | 16 |
| 30670698 | 2019 | Eukaryotic initiation factor 5B (eIF5B) provides a critical cell survival switch to glioblastoma cells via regulation of apoptosis. | 16 |
| 29298419 | 2018 | Oxygen-Sensitive Remodeling of Central Carbon Metabolism by Archaic eIF5B. | 22 |
Citation
Dessen P
EIF5B (eukaryotic translation initiation factor 5B)
Atlas Genet Cytogenet Oncol Haematol. 2018-02-01
Online version: http://atlasgeneticsoncology.org/gene/57365/eif5b-(eukaryotic-translation-initiation-factor-5b)
