ATP5ME (ATP synthase membrane subunit e)

2018-02-01  

Identity

HGNC
ATP5ME
LOCATION
4p16.3
LOCUSID
521
ALIAS
ATP5I,ATP5K

Other Information

Locus ID:

NCBI: 521
MIM: 601519
HGNC: 846
Ensembl: ENSG00000169020

Variants:

dbSNP: 521
ClinVar: 521
TCGA: ENSG00000169020
COSMIC: ATP5ME

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169020ENST00000304312P56385

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
Oxidative phosphorylationKEGGhsa00190
Metabolic pathwaysKEGGhsa01100
F-type ATPase, eukaryotesKEGGhsa_M00158
F-type ATPase, eukaryotesKEGGM00158
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Formation of ATP by chemiosmotic couplingREACTOMER-HSA-163210

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
180608602008Atrazine binds to F1F0-ATP synthase and inhibits mitochondrial function in sperm.9
180608602008Atrazine binds to F1F0-ATP synthase and inhibits mitochondrial function in sperm.9
166820022006F1F0-ATP synthase functions as a co-chaperone of Hsp90-substrate protein complexes.19
166820022006F1F0-ATP synthase functions as a co-chaperone of Hsp90-substrate protein complexes.19
119394122001Antisense of ATP synthase subunit e inhibits the growth of human hepatocellular carcinoma cells.4
119394122001Antisense of ATP synthase subunit e inhibits the growth of human hepatocellular carcinoma cells.4

Citation

Dessen P

ATP5ME (ATP synthase membrane subunit e)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57377/atp5me-(atp-synthase-membrane-subunit-e)