Identity
HGNC
LOCATION
5q35.1
LOCUSID
ALIAS
FAD49,FTHS,HOFI,KIAA1295,TKS4,TSK4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 285590
MIM: 613293
HGNC: 29242
Ensembl: ENSG00000174705
Variants:
dbSNP: 285590
ClinVar: 285590
TCGA: ENSG00000174705
COSMIC: SH3PXD2B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000174705 | ENST00000311601 | A1X283 |
| ENSG00000174705 | ENST00000518522 | H0YAU1 |
| ENSG00000174705 | ENST00000519643 | G3V144 |
| ENSG00000174705 | ENST00000636523 | A0A1B0GUF2 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38672463 | 2024 | Morphological Changes Induced by TKS4 Deficiency Can Be Reversed by EZH2 Inhibition in Colorectal Carcinoma Cells. | 0 |
| 38672463 | 2024 | Morphological Changes Induced by TKS4 Deficiency Can Be Reversed by EZH2 Inhibition in Colorectal Carcinoma Cells. | 0 |
| 36674824 | 2023 | Absence of Scaffold Protein Tks4 Disrupts Several Signaling Pathways in Colon Cancer Cells. | 1 |
| 37211344 | 2023 | Comprehensive bioinformatics and experimental analysis of SH3PXD2B reveals its carcinogenic effect in gastric carcinoma. | 2 |
| 37894817 | 2023 | Studying the Association of TKS4 and CD2AP Scaffold Proteins and Their Implications in the Partial Epithelial-Mesenchymal Transition (EMT) Process. | 1 |
| 36674824 | 2023 | Absence of Scaffold Protein Tks4 Disrupts Several Signaling Pathways in Colon Cancer Cells. | 1 |
| 37211344 | 2023 | Comprehensive bioinformatics and experimental analysis of SH3PXD2B reveals its carcinogenic effect in gastric carcinoma. | 2 |
| 37894817 | 2023 | Studying the Association of TKS4 and CD2AP Scaffold Proteins and Their Implications in the Partial Epithelial-Mesenchymal Transition (EMT) Process. | 1 |
| 30962481 | 2019 | Significance of the Tks4 scaffold protein in bone tissue homeostasis. | 10 |
| 31591456 | 2019 | Enhanced endothelial motility and multicellular sprouting is mediated by the scaffold protein TKS4. | 3 |
| 31671862 | 2019 | Absence of the Tks4 Scaffold Protein Induces Epithelial-Mesenchymal Transition-Like Changes in Human Colon Cancer Cells. | 9 |
| 30962481 | 2019 | Significance of the Tks4 scaffold protein in bone tissue homeostasis. | 10 |
| 31591456 | 2019 | Enhanced endothelial motility and multicellular sprouting is mediated by the scaffold protein TKS4. | 3 |
| 31671862 | 2019 | Absence of the Tks4 Scaffold Protein Induces Epithelial-Mesenchymal Transition-Like Changes in Human Colon Cancer Cells. | 9 |
| 29928795 | 2018 | EGF Regulates the Interaction of Tks4 with Src through Its SH2 and SH3 Domains. | 14 |
Citation
Dessen P
SH3PXD2B (SH3 and PX domains 2B)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57400/sh3pxd2b-(sh3-and-px-domains-2b)
