MRTFB (myocardin related transcription factor B)

2018-07-01  

Identity

HGNC
LOCATION
16p13.12
LOCUSID
ALIAS
MKL2,MRTF-B,NPD001

Other Information

Locus ID:

NCBI: 57496
MIM: 609463
HGNC: 29819
Ensembl: ENSG00000186260

Variants:

dbSNP: 57496
ClinVar: 57496
TCGA: ENSG00000186260
COSMIC: MRTFB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186260ENST00000318282Q9ULH7
ENSG00000186260ENST00000571589Q9ULH7
ENSG00000186260ENST00000571770I3L2A0
ENSG00000186260ENST00000572567I3L2S3
ENSG00000186260ENST00000573051Q9ULH7
ENSG00000186260ENST00000573434I3L3Z7
ENSG00000186260ENST00000574045Q9ULH7
ENSG00000186260ENST00000574998I3L0U1

References

Pubmed IDYearTitleCitations
385824472024KLF15 maintains contractile phenotype of vascular smooth muscle cells and prevents thoracic aortic dissection by interacting with MRTFB.0
385824472024KLF15 maintains contractile phenotype of vascular smooth muscle cells and prevents thoracic aortic dissection by interacting with MRTFB.0
370139002023De novo variants in MRTFB have gain-of-function activity in Drosophila and are associated with a novel neurodevelopmental phenotype with dysmorphic features.1
371646932023Role of CRP2-MRTF interaction in functions of myofibroblasts.2
370139002023De novo variants in MRTFB have gain-of-function activity in Drosophila and are associated with a novel neurodevelopmental phenotype with dysmorphic features.1
371646932023Role of CRP2-MRTF interaction in functions of myofibroblasts.2
352161782022Oxidative Stress Enhances the TGF-β2-RhoA-MRTF-A/B Axis in Cells Entering Endothelial-Mesenchymal Transition.4
352161782022Oxidative Stress Enhances the TGF-β2-RhoA-MRTF-A/B Axis in Cells Entering Endothelial-Mesenchymal Transition.4
328242972020The New Model of Snail Expression Regulation: The Role of MRTFs in Fast and Slow Endothelial-Mesenchymal Transition.8
328242972020The New Model of Snail Expression Regulation: The Role of MRTFs in Fast and Slow Endothelial-Mesenchymal Transition.8
316906632019MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM.16
316906632019MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM.16
293354312018Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology.4
299127152018Ectomesenchymal Chondromyxoid Tumor: A Neoplasm Characterized by Recurrent RREB1-MKL2 Fusions.21
303322842018Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by MKL2, ternary complex factors, and actin dynamics.3

Citation

Dessen P

MRTFB (myocardin related transcription factor B)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57410/mrtfb-(myocardin-related-transcription-factor-b)