Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84612
MIM: 608975
HGNC: 16245
Ensembl: ENSG00000124171
Variants:
dbSNP: 84612
ClinVar: 84612
TCGA: ENSG00000124171
COSMIC: PARD6B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000124171 | ENST00000371610 | Q9BYG5 |
| ENSG00000124171 | ENST00000396039 | Q9BYG5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28652146 | 2017 | Downregulation of PKCζ/Pard3/Pard6b is responsible for lung adenocarcinoma cell EMT and invasion. | 20 |
| 28652146 | 2017 | Downregulation of PKCζ/Pard3/Pard6b is responsible for lung adenocarcinoma cell EMT and invasion. | 20 |
| 26526116 | 2016 | The localisation of the apical Par/Cdc42 polarity module is specifically affected in microvillus inclusion disease. | 19 |
| 26526116 | 2016 | The localisation of the apical Par/Cdc42 polarity module is specifically affected in microvillus inclusion disease. | 19 |
| 25662318 | 2015 | Functional cross-talk between Cdc42 and two downstream targets, Par6B and PAK4. | 15 |
| 25662318 | 2015 | Functional cross-talk between Cdc42 and two downstream targets, Par6B and PAK4. | 15 |
| 21300793 | 2011 | Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis. | 77 |
| 21300793 | 2011 | Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis. | 77 |
| 20631255 | 2010 | Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B. | 45 |
| 20631255 | 2010 | Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B. | 45 |
| 19401335 | 2009 | Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells. | 86 |
| 19401335 | 2009 | Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells. | 86 |
| 15677324 | 2005 | Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator. | 61 |
| 15677324 | 2005 | Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator. | 61 |
Citation
Dessen P
PARD6B (par-6 family cell polarity regulator beta)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57411/pard6b-(par-6-family-cell-polarity-regulator-beta)
