NCS1 (neuronal calcium sensor 1)

2018-07-01  

Identity

HGNC
LOCATION
9q34.11
LOCUSID
ALIAS
FLUP,FREQ
FUSION GENES

Other Information

Locus ID:

NCBI: 23413
MIM: 603315
HGNC: 3953
Ensembl: ENSG00000107130

Variants:

dbSNP: 23413
ClinVar: 23413
TCGA: ENSG00000107130
COSMIC: NCS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107130ENST00000372398P62166
ENSG00000107130ENST00000372398A0A024R8B2
ENSG00000107130ENST00000630865P62166

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385641622024NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells.0
385641622024NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells.0
380629642023[Neuronal Calcium Sensor-1: A Zinc/Redox-Dependent Protein of Nervous System Signaling Pathways].0
380629642023[Neuronal Calcium Sensor-1: A Zinc/Redox-Dependent Protein of Nervous System Signaling Pathways].0
329363122021Disorder in a two-domain neuronal Ca(2+)-binding protein regulates domain stability and dynamics using ligand mimicry.2
348304872021Disulfide Dimerization of Neuronal Calcium Sensor-1: Implications for Zinc and Redox Signaling.6
329363122021Disorder in a two-domain neuronal Ca(2+)-binding protein regulates domain stability and dynamics using ligand mimicry.2
348304872021Disulfide Dimerization of Neuronal Calcium Sensor-1: Implications for Zinc and Redox Signaling.6
316476022020NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin.7
319730692020Membrane Binding of Neuronal Calcium Sensor-1: Highly Specific Interaction with Phosphatidylinositol-3-Phosphate.4
322396152020Neuronal Calcium Sensor 1 is up-regulated in response to stress to promote cell survival and motility in cancer cells.15
316476022020NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin.7
319730692020Membrane Binding of Neuronal Calcium Sensor-1: Highly Specific Interaction with Phosphatidylinositol-3-Phosphate.4
322396152020Neuronal Calcium Sensor 1 is up-regulated in response to stress to promote cell survival and motility in cancer cells.15
317049462019Cav2.3 channels contribute to dopaminergic neuron loss in a model of Parkinson's disease.40

Citation

Dessen P

NCS1 (neuronal calcium sensor 1)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57425/ncs1-(neuronal-calcium-sensor-1)