Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10724
MIM: 604039
HGNC: 7056
Ensembl: ENSG00000198408
Variants:
dbSNP: 10724
ClinVar: 10724
TCGA: ENSG00000198408
COSMIC: OGA
RNA/Proteins
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Insulin resistance | KEGG | hsa04931 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37907462 | 2023 | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. | 3 |
| 37907462 | 2023 | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. | 3 |
| 36124999 | 2022 | Inhibition of O-GlcNAcase Inhibits Hematopoietic and Leukemic Stem Cell Self-Renewal and Drives Dendritic Cell Differentiation via STAT3/5 Signaling. | 11 |
| 36124999 | 2022 | Inhibition of O-GlcNAcase Inhibits Hematopoietic and Leukemic Stem Cell Self-Renewal and Drives Dendritic Cell Differentiation via STAT3/5 Signaling. | 11 |
| 32365408 | 2021 | Pharmacological inhibition and knockdown of O-GlcNAcase reduces cellular internalization of α-synuclein preformed fibrils. | 17 |
| 33310751 | 2021 | Bacterial O-GlcNAcase genes abundance decreases in ulcerative colitis patients and its administration ameliorates colitis in mice. | 15 |
| 33333092 | 2021 | Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe. | 9 |
| 34135314 | 2021 | OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair. | 6 |
| 32365408 | 2021 | Pharmacological inhibition and knockdown of O-GlcNAcase reduces cellular internalization of α-synuclein preformed fibrils. | 17 |
| 33310751 | 2021 | Bacterial O-GlcNAcase genes abundance decreases in ulcerative colitis patients and its administration ameliorates colitis in mice. | 15 |
| 33333092 | 2021 | Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe. | 9 |
| 34135314 | 2021 | OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair. | 6 |
| 31501520 | 2020 | O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth. | 25 |
| 33086728 | 2020 | Involvement of NDPK-B in Glucose Metabolism-Mediated Endothelial Damage via Activation of the Hexosamine Biosynthesis Pathway and Suppression of O-GlcNAcase Activity. | 8 |
| 31501520 | 2020 | O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth. | 25 |
Citation
Dessen P
OGA (O-GlcNAcase)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57432
