Identity
HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
ARE1,SAC2,SACM2L,dJ1033B10.5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6293
MIM: 603443
HGNC: 10518
Ensembl: ENSG00000223501
Variants:
dbSNP: 6293
ClinVar: 6293
TCGA: ENSG00000223501
COSMIC: VPS52
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000223501 | ENST00000445902 | Q8N1B4 |
| ENSG00000223501 | ENST00000445902 | Q4VXZ2 |
| ENSG00000223501 | ENST00000482399 | E9PI03 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31533953 | 2019 | The PI(4)P phosphatase Sac2 controls insulin granule docking and release. | 11 |
| 31533953 | 2019 | The PI(4)P phosphatase Sac2 controls insulin granule docking and release. | 11 |
| 27889639 | 2017 | Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission. | 30 |
| 28791438 | 2017 | VPS52 induces apoptosis via cathepsin D in gastric cancer. | 9 |
| 27889639 | 2017 | Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission. | 30 |
| 28791438 | 2017 | VPS52 induces apoptosis via cathepsin D in gastric cancer. | 9 |
| 25269472 | 2014 | p62/SQSTM1 is involved in cisplatin resistance in human ovarian cancer cells via the Keap1-Nrf2-ARE system. | 44 |
| 25269472 | 2014 | p62/SQSTM1 is involved in cisplatin resistance in human ovarian cancer cells via the Keap1-Nrf2-ARE system. | 44 |
| 19620288 | 2009 | Dual roles of the mammalian GARP complex in tethering and SNARE complex assembly at the trans-golgi network. | 71 |
| 19851445 | 2009 | High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. | 58 |
| 19620288 | 2009 | Dual roles of the mammalian GARP complex in tethering and SNARE complex assembly at the trans-golgi network. | 71 |
| 19851445 | 2009 | High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. | 58 |
| 18367545 | 2008 | Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes. | 77 |
| 18367545 | 2008 | Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes. | 77 |
| 15878329 | 2005 | Characterization of the human GARP (Golgi associated retrograde protein) complex. | 55 |
Citation
Dessen P
VPS52 (VPS52 subunit of GARP complex)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57433/vps52-(vps52-subunit-of-garp-complex)
