Identity
HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
HUSSY-08,IscS,NIFS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9054
MIM: 603485
HGNC: 15910
Ensembl: ENSG00000244005
Variants:
dbSNP: 9054
ClinVar: 9054
TCGA: ENSG00000244005
COSMIC: NFS1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35221331 | 2022 | Phosphorylated NFS1 weakens oxaliplatin-based chemosensitivity of colorectal cancer by preventing PANoptosis. | 68 |
| 35221331 | 2022 | Phosphorylated NFS1 weakens oxaliplatin-based chemosensitivity of colorectal cancer by preventing PANoptosis. | 68 |
| 30817134 | 2019 | Analysis of the Cellular Roles of MOCS3 Identifies a MOCS3-Independent Localization of NFS1 at the Tips of the Centrosome. | 5 |
| 31101807 | 2019 | Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism. | 62 |
| 30817134 | 2019 | Analysis of the Cellular Roles of MOCS3 Identifies a MOCS3-Independent Localization of NFS1 at the Tips of the Centrosome. | 5 |
| 31101807 | 2019 | Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism. | 62 |
| 29983374 | 2018 | Architectural Features of Human Mitochondrial Cysteine Desulfurase Complexes from Crosslinking Mass Spectrometry and Small-Angle X-Ray Scattering. | 9 |
| 30031876 | 2018 | Zinc(II) binding on human wild-type ISCU and Met140 variants modulates NFS1 desulfurase activity. | 11 |
| 29983374 | 2018 | Architectural Features of Human Mitochondrial Cysteine Desulfurase Complexes from Crosslinking Mass Spectrometry and Small-Angle X-Ray Scattering. | 9 |
| 30031876 | 2018 | Zinc(II) binding on human wild-type ISCU and Met140 variants modulates NFS1 desulfurase activity. | 11 |
| 28001042 | 2017 | Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis. | 56 |
| 28271877 | 2017 | The N-Terminus of Iron-Sulfur Cluster Assembly Factor ISD11 Is Crucial for Subcellular Targeting and Interaction with l-Cysteine Desulfurase NFS1. | 9 |
| 28634302 | 2017 | Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions. | 79 |
| 28766335 | 2017 | Functional Complementation Studies Reveal Different Interaction Partners of Escherichia coli IscS and Human NFS1. | 5 |
| 29168506 | 2017 | NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis. | 313 |
Citation
Dessen P
NFS1 (NFS1 cysteine desulfurase)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57449/nfs1-(nfs1-cysteine-desulfurase)
