ZKSCAN4 (zinc finger with KRAB and SCAN domains 4)

2018-07-01  

Identity

HGNC
ZKSCAN4
LOCATION
6p22.1
LOCUSID
387032
ALIAS
P1P373C6,ZNF307,ZNF427,ZSCAN36

Other Information

Locus ID:

NCBI: 387032
MIM: 611643
HGNC: 13854
Ensembl: ENSG00000187626

Variants:

dbSNP: 387032
ClinVar: 387032
TCGA: ENSG00000187626
COSMIC: ZKSCAN4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187626ENST00000377294Q969J2
ENSG00000187626ENST00000377294A0A0S2Z658

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
282234772017ZNF307 (Zinc Finger Protein 307) Acts as a Negative Regulator of Pressure Overload-Induced Cardiac Hypertrophy.3
287659502017Zinc finger protein 307 functions as a tumor‑suppressor and inhibits cell proliferation by inducing apoptosis in hepatocellular carcinoma.7
282234772017ZNF307 (Zinc Finger Protein 307) Acts as a Negative Regulator of Pressure Overload-Induced Cardiac Hypertrophy.3
287659502017Zinc finger protein 307 functions as a tumor‑suppressor and inhibits cell proliferation by inducing apoptosis in hepatocellular carcinoma.7
190083342009A RAS recruitment screen identifies ZKSCAN4 as a glucocorticoid receptor-interacting protein.6
190083342009A RAS recruitment screen identifies ZKSCAN4 as a glucocorticoid receptor-interacting protein.6
179109482007ZNF307, a novel zinc finger gene suppresses p53 and p21 pathway.13
179109482007ZNF307, a novel zinc finger gene suppresses p53 and p21 pathway.13

Citation

Dessen P

ZKSCAN4 (zinc finger with KRAB and SCAN domains 4)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57470/zkscan4-(zinc-finger-with-krab-and-scan-domains-4)