Identity
HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
LAT2,LPI-PC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23428
MIM: 604235
HGNC: 11066
Ensembl: ENSG00000092068
Variants:
dbSNP: 23428
ClinVar: 23428
TCGA: ENSG00000092068
COSMIC: SLC7A8
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38244585 | 2024 | SLC7A8 overexpression inhibits the growth and metastasis of lung adenocarcinoma and is correlated with a dismal prognosis. | 3 |
| 38890684 | 2024 | Evidence for a relationship between genetic polymorphisms of the L-DOPA transporter LAT2/4F2hc and risk of hypertension in the context of chronic kidney disease. | 0 |
| 38244585 | 2024 | SLC7A8 overexpression inhibits the growth and metastasis of lung adenocarcinoma and is correlated with a dismal prognosis. | 3 |
| 38890684 | 2024 | Evidence for a relationship between genetic polymorphisms of the L-DOPA transporter LAT2/4F2hc and risk of hypertension in the context of chronic kidney disease. | 0 |
| 36626488 | 2022 | Identification and verification of microRNA signature and key genes in the development of osteosarcoma with lung metastasis. | 0 |
| 36626488 | 2022 | Identification and verification of microRNA signature and key genes in the development of osteosarcoma with lung metastasis. | 0 |
| 34494553 | 2021 | Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma. | 7 |
| 34494553 | 2021 | Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma. | 7 |
| 31701662 | 2020 | Abnormalities in the genes that encode Large Amino Acid Transporters increase the risk of Autism Spectrum Disorder. | 26 |
| 32200487 | 2020 | The solute carrier SLC7A8 is a marker of favourable prognosis in ER-positive low proliferative invasive breast cancer. | 10 |
| 32993041 | 2020 | Sub-Nanometer Cryo-EM Density Map of the Human Heterodimeric Amino Acid Transporter 4F2hc-LAT2. | 7 |
| 33001560 | 2020 | Small molecule inhibitors provide insights into the relevance of LAT1 and LAT2 in materno-foetal amino acid transport. | 6 |
| 33066406 | 2020 | The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2. | 14 |
| 31701662 | 2020 | Abnormalities in the genes that encode Large Amino Acid Transporters increase the risk of Autism Spectrum Disorder. | 26 |
| 32200487 | 2020 | The solute carrier SLC7A8 is a marker of favourable prognosis in ER-positive low proliferative invasive breast cancer. | 10 |
Citation
Dessen P
SLC7A8 (solute carrier family 7 member 8)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57472/slc7a8-(solute-carrier-family-7-member-8)
