Identity
HGNC
LOCATION
10q24.1
LOCUSID
ALIAS
CAP,FLAF2,R85FL,SH3D5,SH3P12,SORB1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10580
MIM: 605264
HGNC: 14565
Ensembl: ENSG00000095637
Variants:
dbSNP: 10580
ClinVar: 10580
TCGA: ENSG00000095637
COSMIC: SORBS1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38212723 | 2024 | Increased serum extrachromosomal circular DNA SORBS1(circle) level is associated with insulin resistance in patients with newly diagnosed type 2 diabetes mellitus. | 3 |
| 38915053 | 2024 | circSORBS1 inhibits lung cancer progression by sponging miR-6779-5p and directly binding RUFY3 mRNA. | 0 |
| 38212723 | 2024 | Increased serum extrachromosomal circular DNA SORBS1(circle) level is associated with insulin resistance in patients with newly diagnosed type 2 diabetes mellitus. | 3 |
| 38915053 | 2024 | circSORBS1 inhibits lung cancer progression by sponging miR-6779-5p and directly binding RUFY3 mRNA. | 0 |
| 36854874 | 2023 | Down-regulation and clinical significance of Sorbin and SH3 domain-containing protein 1 in bladder cancer tissues. | 2 |
| 37164919 | 2023 | MiR-223-3p increases resistance of colorectal cancer cells to 5-fluorouracil via targeting SORBS1. | 1 |
| 36854874 | 2023 | Down-regulation and clinical significance of Sorbin and SH3 domain-containing protein 1 in bladder cancer tissues. | 2 |
| 37164919 | 2023 | MiR-223-3p increases resistance of colorectal cancer cells to 5-fluorouracil via targeting SORBS1. | 1 |
| 35107206 | 2022 | A variation in SORBS1 is associated with type 2 diabetes and high-density lipoprotein cholesterol in Chinese population. | 4 |
| 35196185 | 2022 | MicroRNA miR-3646 promotes malignancy of lung adenocarcinoma cells by suppressing sorbin and SH3 domain-containing protein 1 via the c-Jun NH2-terminal kinase signaling pathway. | 1 |
| 35107206 | 2022 | A variation in SORBS1 is associated with type 2 diabetes and high-density lipoprotein cholesterol in Chinese population. | 4 |
| 35196185 | 2022 | MicroRNA miR-3646 promotes malignancy of lung adenocarcinoma cells by suppressing sorbin and SH3 domain-containing protein 1 via the c-Jun NH2-terminal kinase signaling pathway. | 1 |
| 34409913 | 2021 | Screening differentially expressed genes between endometriosis and ovarian cancer to find new biomarkers for endometriosis. | 13 |
| 34409913 | 2021 | Screening differentially expressed genes between endometriosis and ovarian cancer to find new biomarkers for endometriosis. | 13 |
| 32319594 | 2020 | SORBS1 serves a metastatic role via suppression of AHNAK in colorectal cancer cell lines. | 15 |
Citation
Dessen P
SORBS1 (sorbin and SH3 domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57478/chromosome-explorer/submit-meetings/
