Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2352
MIM: 602469
HGNC: 3795
Ensembl: ENSG00000110203
Variants:
dbSNP: 2352
ClinVar: 2352
TCGA: ENSG00000110203
COSMIC: FOLR3
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10810 | pemetrexed | Chemical | ClinicalAnnotation | associated | PD | 24732178 | |
| PA443622 | Carcinoma, Non-Small-Cell Lung | Disease | ClinicalAnnotation | associated | PD | 24732178 | |
| PA444937 | Mesothelioma | Disease | ClinicalAnnotation | associated | PD | 24732178 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38273401 | 2024 | Blood FOLR3 methylation dysregulations and heterogeneity in non-small lung cancer highlight its strong associations with lung squamous carcinoma. | 0 |
| 38273401 | 2024 | Blood FOLR3 methylation dysregulations and heterogeneity in non-small lung cancer highlight its strong associations with lung squamous carcinoma. | 0 |
| 37756380 | 2023 | Secreted folate receptor γ drives fibrogenesis in metabolic dysfunction-associated steatohepatitis by amplifying TGFβ signaling in hepatic stellate cells. | 2 |
| 37756380 | 2023 | Secreted folate receptor γ drives fibrogenesis in metabolic dysfunction-associated steatohepatitis by amplifying TGFβ signaling in hepatic stellate cells. | 2 |
| 36192006 | 2022 | A Novel Immunomodulatory Mechanism by Which Vitamin D Influences Folate Receptor 3 Expression to Reduce COVID-19 Severity. | 2 |
| 36192006 | 2022 | A Novel Immunomodulatory Mechanism by Which Vitamin D Influences Folate Receptor 3 Expression to Reduce COVID-19 Severity. | 2 |
| 33634983 | 2021 | A folate receptor 3 SNP promotes mitochondria-induced clonogenicity of CML leukemia cells: Implications for treatment free remission. | 4 |
| 33634983 | 2021 | A folate receptor 3 SNP promotes mitochondria-induced clonogenicity of CML leukemia cells: Implications for treatment free remission. | 4 |
| 32581311 | 2020 | Plasma Homocysteine Concentration is Associated with the Expression Level of Folate Receptor 3. | 7 |
| 32581311 | 2020 | Plasma Homocysteine Concentration is Associated with the Expression Level of Folate Receptor 3. | 7 |
| 28948692 | 2017 | Mutations in folate transporter genes and risk for human myelomeningocele. | 12 |
| 28948692 | 2017 | Mutations in folate transporter genes and risk for human myelomeningocele. | 12 |
| 20634891 | 2010 | Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. | 28 |
| 20683905 | 2010 | Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele. | 18 |
| 20683905 | 2010 | Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele. | 18 |
Citation
Dessen P
FOLR3 (folate receptor gamma)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57515/folr3-(folate-receptor-gamma)
