STON2 (stonin 2)

2018-07-01  

Identity

HGNC
LOCATION
14q31.1
LOCUSID
ALIAS
STN2,STNB,STNB2
FUSION GENES

Other Information

Locus ID:

NCBI: 85439
MIM: 608467
HGNC: 30652
Ensembl: ENSG00000140022

Variants:

dbSNP: 85439
ClinVar: 85439
TCGA: ENSG00000140022
COSMIC: STON2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140022ENST00000553821H0YJ05
ENSG00000140022ENST00000555447Q8WXE9
ENSG00000140022ENST00000557055G3V322
ENSG00000140022ENST00000614646Q8WXE9
ENSG00000140022ENST00000649389A0A3B3IU55

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Clathrin-mediated endocytosisREACTOMER-HSA-8856828
Cargo recognition for clathrin-mediated endocytosisREACTOMER-HSA-8856825

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
367024392023Stonin 2 activates lysosomal-mTOR axis for cell survival in oral cancer.0
367024392023Stonin 2 activates lysosomal-mTOR axis for cell survival in oral cancer.0
325751072020Narrowing down the Common Cytogenetic Deletion 14q to a 5.6-Mb Critical Region in 1p/19q Codeletion Oligodendroglioma-Relapsed Patients Points to Two Potential Relapse-Related Genes: SEL1L and STON2.3
327374152020Keratoconus-susceptibility gene identification by corneal thickness genome-wide association study and artificial intelligence IBM Watson.14
325751072020Narrowing down the Common Cytogenetic Deletion 14q to a 5.6-Mb Critical Region in 1p/19q Codeletion Oligodendroglioma-Relapsed Patients Points to Two Potential Relapse-Related Genes: SEL1L and STON2.3
327374152020Keratoconus-susceptibility gene identification by corneal thickness genome-wide association study and artificial intelligence IBM Watson.14
303255822019miR-199b-5p-Stonin 2 axis regulates metastases and epithelial-to-mesenchymal transition of papillary thyroid carcinoma.11
303255822019miR-199b-5p-Stonin 2 axis regulates metastases and epithelial-to-mesenchymal transition of papillary thyroid carcinoma.11
305184242018STON2 negatively modulates stem-like properties in ovarian cancer cells via DNMT1/MUC1 pathway.11
305184242018STON2 negatively modulates stem-like properties in ovarian cancer cells via DNMT1/MUC1 pathway.11
287589392017Stonin 2 Overexpression is Correlated with Unfavorable Prognosis and Tumor Invasion in Epithelial Ovarian Cancer.12
287589392017Stonin 2 Overexpression is Correlated with Unfavorable Prognosis and Tumor Invasion in Epithelial Ovarian Cancer.12
237853972013Cortical surface area correlates with STON2 gene Ser307Pro polymorphism in first-episode treatment-naïve patients with schizophrenia.4
237853972013Cortical surface area correlates with STON2 gene Ser307Pro polymorphism in first-episode treatment-naïve patients with schizophrenia.4
214071392011Positive association of the human STON2 gene with schizophrenia.11

Citation

Dessen P

STON2 (stonin 2)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57526/ston2-(stonin-2)