Identity
HGNC
LOCATION
13q14.2
LOCUSID
ALIAS
C13orf4,CLLD8,CLLL8,KMT1F
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 83852
MIM: 607865
HGNC: 20263
Ensembl: ENSG00000136169
Variants:
dbSNP: 83852
ClinVar: 83852
TCGA: ENSG00000136169
COSMIC: SETDB2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000136169 | ENST00000258672 | X6R383 |
| ENSG00000136169 | ENST00000317257 | Q96T68 |
| ENSG00000136169 | ENST00000354234 | Q96T68 |
| ENSG00000136169 | ENST00000611815 | A0A087WYZ9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38159574 | 2024 | Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46. | 0 |
| 38159574 | 2024 | Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46. | 0 |
| 36504353 | 2023 | Histone lysine methyltransferase SETDB2 suppresses NRF2 to restrict tumor progression and modulates chemotherapy sensitivity in lung adenocarcinoma. | 3 |
| 36504353 | 2023 | Histone lysine methyltransferase SETDB2 suppresses NRF2 to restrict tumor progression and modulates chemotherapy sensitivity in lung adenocarcinoma. | 3 |
| 34479991 | 2021 | Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2. | 16 |
| 34479991 | 2021 | Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2. | 16 |
| 30850015 | 2019 | Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming. | 35 |
| 31350176 | 2019 | The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair. | 49 |
| 30850015 | 2019 | Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming. | 35 |
| 31350176 | 2019 | The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair. | 49 |
| 29234167 | 2018 | The SETDB2 locus: evidence for a genetic link between handedness and atopic disease. | 4 |
| 29694893 | 2018 | SETDB2 Links E2A-PBX1 to Cell-Cycle Dysregulation in Acute Leukemia through CDKN2C Repression. | 13 |
| 29234167 | 2018 | The SETDB2 locus: evidence for a genetic link between handedness and atopic disease. | 4 |
| 29694893 | 2018 | SETDB2 Links E2A-PBX1 to Cell-Cycle Dysregulation in Acute Leukemia through CDKN2C Repression. | 13 |
| 29099276 | 2017 | SETDB2 and RIOX2 are differentially expressed among renal cell tumor subtypes, associating with prognosis and metastization. | 14 |
Citation
Dessen P
SETDB2 (SET domain bifurcated histone lysine methyltransferase 2)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57538/setdb2-(set-domain-bifurcated-histone-lysine-methyltransferase-2)
