Identity
HGNC
LOCATION
17p12
LOCUSID
ALIAS
NPC-A-10,RICH2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9912
MIM: 617716
HGNC: 29096
Ensembl: ENSG00000006740
Variants:
dbSNP: 9912
ClinVar: 9912
TCGA: ENSG00000006740
COSMIC: ARHGAP44
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37926169 | 2023 | RICH2 decreases the mitochondrial number and affects mitochondrial localization in diffuse low-grade glioma-related epilepsy. | 0 |
| 38031136 | 2023 | ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells. | 0 |
| 37926169 | 2023 | RICH2 decreases the mitochondrial number and affects mitochondrial localization in diffuse low-grade glioma-related epilepsy. | 0 |
| 38031136 | 2023 | ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells. | 0 |
| 33223223 | 2021 | CD317 mediates immunocytolysis resistance by RICH2/cytoskeleton-dependent membrane protection. | 3 |
| 33223223 | 2021 | CD317 mediates immunocytolysis resistance by RICH2/cytoskeleton-dependent membrane protection. | 3 |
| 31136984 | 2019 | RICH2, a potential tumor suppressor in hepatocellular carcinoma. | 4 |
| 31136984 | 2019 | RICH2, a potential tumor suppressor in hepatocellular carcinoma. | 4 |
| 28069446 | 2017 | RICH2 is implicated in viraemic control of HIV-1 in black South African individuals. | 2 |
| 28527113 | 2017 | Mutant p53 promotes cell spreading and migration via ARHGAP44. | 10 |
| 28069446 | 2017 | RICH2 is implicated in viraemic control of HIV-1 in black South African individuals. | 2 |
| 28527113 | 2017 | Mutant p53 promotes cell spreading and migration via ARHGAP44. | 10 |
| 21107268 | 2011 | Screening low-frequency SNPS from genome-wide association study reveals a new risk allele for progression to AIDS. | 16 |
| 21107268 | 2011 | Screening low-frequency SNPS from genome-wide association study reveals a new risk allele for progression to AIDS. | 16 |
| 19273615 | 2009 | A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells. | 82 |
Citation
Dessen P
ARHGAP44 (Rho GTPase activating protein 44)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57539/arhgap44-(rho-gtpase-activating-protein-44)
