Identity
HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
CD367,CLECSF6,DCIR,DDB27,HDCGC13P,LLIR,hDCIR
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 50856
MIM: 605306
HGNC: 13257
Ensembl: ENSG00000284697
Variants:
dbSNP: 50856
ClinVar: 50856
TCGA: ENSG00000284697
COSMIC: CLEC4A
RNA/Proteins
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| C-type lectin receptors (CLRs) | REACTOME | R-HSA-5621481 |
| Dectin-2 family | REACTOME | R-HSA-5621480 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38532110 | 2024 | The C-type lectin DCIR contributes to the immune response and pathogenesis of colorectal cancer. | 0 |
| 38532110 | 2024 | The C-type lectin DCIR contributes to the immune response and pathogenesis of colorectal cancer. | 0 |
| 37266426 | 2023 | DCIR suppresses osteoclastic proliferation and resorption by downregulating M-CSF and RANKL signaling. | 0 |
| 37266426 | 2023 | DCIR suppresses osteoclastic proliferation and resorption by downregulating M-CSF and RANKL signaling. | 0 |
| 36323738 | 2022 | Differential expression of immune-regulatory proteins C5AR1, CLEC4A and NLRP3 on peripheral blood mononuclear cells in early-stage non-small cell lung cancer patients. | 5 |
| 36323738 | 2022 | Differential expression of immune-regulatory proteins C5AR1, CLEC4A and NLRP3 on peripheral blood mononuclear cells in early-stage non-small cell lung cancer patients. | 5 |
| 34817551 | 2021 | DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis. | 10 |
| 34817551 | 2021 | DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis. | 10 |
| 32415968 | 2020 | Pivotal role of the carbohydrate recognition domain in self-interaction of CLEC4A to elicit the ITIM-mediated inhibitory function in murine conventional dendritic cells in vitro. | 6 |
| 32415968 | 2020 | Pivotal role of the carbohydrate recognition domain in self-interaction of CLEC4A to elicit the ITIM-mediated inhibitory function in murine conventional dendritic cells in vitro. | 6 |
| 29146595 | 2018 | The cartilage-specific lectin C-type lectin domain family 3 member A (CLEC3A) enhances tissue plasminogen activator-mediated plasminogen activation. | 11 |
| 29146595 | 2018 | The cartilage-specific lectin C-type lectin domain family 3 member A (CLEC3A) enhances tissue plasminogen activator-mediated plasminogen activation. | 11 |
| 26429306 | 2015 | Contribution of dendritic cell immunoreceptor (DCIR) polymorphisms in susceptibility of systemic lupus erythematosus and primary Sjogren's syndrome. | 6 |
| 26429306 | 2015 | Contribution of dendritic cell immunoreceptor (DCIR) polymorphisms in susceptibility of systemic lupus erythematosus and primary Sjogren's syndrome. | 6 |
| 24239607 | 2014 | DCIR interacts with ligands from both endogenous and pathogenic origin. | 28 |
Citation
Dessen P
CLEC4A (C-type lectin domain family 4 member A)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57543/clec4a-(c-type-lectin-domain-family-4-member-a)
