MIR1281 (microRNA 1281)

2018-07-01 Affiliation

Identity

HGNC

MIR1281

LOCATION

22q13.2

LOCUSID

100302237

ALIAS

MIRN1281,hsa-mir-1281

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 100302237
HGNC: 35359
Ensembl: ENSG00000284015
miRBase:

Variants:

dbSNP: 100302237
ClinVar: 100302237
TCGA: ENSG00000284015
COSMIC: MIR1281

RNA/Proteins

Pathways

Pathway	Source	External ID
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Disease	REACTOME	R-HSA-1643685
Diseases of signal transduction	REACTOME	R-HSA-5663202
Signaling by NOTCH1 in Cancer	REACTOME	R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer	REACTOME	R-HSA-2644602
Constitutive Signaling by NOTCH1 PEST Domain Mutants	REACTOME	R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	REACTOME	R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	REACTOME	R-HSA-2894862
Immune System	REACTOME	R-HSA-168256
Innate Immune System	REACTOME	R-HSA-168249
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways	REACTOME	R-HSA-168928
TRAF3-dependent IRF activation pathway	REACTOME	R-HSA-918233
TRAF6 mediated IRF7 activation	REACTOME	R-HSA-933541
Cytosolic sensors of pathogen-associated DNA	REACTOME	R-HSA-1834949
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	REACTOME	R-HSA-3134973
C-type lectin receptors (CLRs)	REACTOME	R-HSA-5621481
CD209 (DC-SIGN) signaling	REACTOME	R-HSA-5621575
Hemostasis	REACTOME	R-HSA-109582
Factors involved in megakaryocyte development and platelet production	REACTOME	R-HSA-983231
Signal Transduction	REACTOME	R-HSA-162582
Signaling by NOTCH	REACTOME	R-HSA-157118
Pre-NOTCH Expression and Processing	REACTOME	R-HSA-1912422
Pre-NOTCH Transcription and Translation	REACTOME	R-HSA-1912408
Signaling by NOTCH1	REACTOME	R-HSA-1980143
NOTCH1 Intracellular Domain Regulates Transcription	REACTOME	R-HSA-2122947
Signaling by NOTCH2	REACTOME	R-HSA-1980145
NOTCH2 intracellular domain regulates transcription	REACTOME	R-HSA-2197563
Signaling by Wnt	REACTOME	R-HSA-195721
TCF dependent signaling in response to WNT	REACTOME	R-HSA-201681
Formation of the beta-catenin:TCF transactivating complex	REACTOME	R-HSA-201722
Gene Expression	REACTOME	R-HSA-74160
Generic Transcription Pathway	REACTOME	R-HSA-212436
Transcriptional Regulation by TP53	REACTOME	R-HSA-3700989
Epigenetic regulation of gene expression	REACTOME	R-HSA-212165
Cell Cycle	REACTOME	R-HSA-1640170
Cell Cycle, Mitotic	REACTOME	R-HSA-69278
Mitotic G2-G2/M phases	REACTOME	R-HSA-453274
G2/M Transition	REACTOME	R-HSA-69275
Polo-like kinase mediated events	REACTOME	R-HSA-156711
Circadian Clock	REACTOME	R-HSA-400253
BMAL1:CLOCK,NPAS2 activates circadian gene expression	REACTOME	R-HSA-1368108
RORA activates gene expression	REACTOME	R-HSA-1368082
Metabolism	REACTOME	R-HSA-1430728
Metabolism of lipids and lipoproteins	REACTOME	R-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolism	REACTOME	R-HSA-535734
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	REACTOME	R-HSA-400206
PPARA activates gene expression	REACTOME	R-HSA-1989781
Developmental Biology	REACTOME	R-HSA-1266738
Transcriptional regulation of white adipocyte differentiation	REACTOME	R-HSA-381340
DNA Repair	REACTOME	R-HSA-73894
Cellular responses to stress	REACTOME	R-HSA-2262752
Cellular response to hypoxia	REACTOME	R-HSA-2262749
Regulation of Hypoxia-inducible Factor (HIF) by oxygen	REACTOME	R-HSA-1234174
Regulation of gene expression by Hypoxia-inducible Factor	REACTOME	R-HSA-1234158
Cellular response to heat stress	REACTOME	R-HSA-3371556
HSF1-dependent transactivation	REACTOME	R-HSA-3371571
Attenuation phase	REACTOME	R-HSA-3371568
Chromatin organization	REACTOME	R-HSA-4839726
Chromatin modifying enzymes	REACTOME	R-HSA-3247509
HATs acetylate histones	REACTOME	R-HSA-3214847
Nucleotide Excision Repair	REACTOME	R-HSA-5696398
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	REACTOME	R-HSA-6781827
Formation of TC-NER Pre-Incision Complex	REACTOME	R-HSA-6781823
Dual incision in TC-NER	REACTOME	R-HSA-6782135
Gap-filling DNA repair synthesis and ligation in TC-NER	REACTOME	R-HSA-6782210
Positive epigenetic regulation of rRNA expression	REACTOME	R-HSA-5250913
B-WICH complex positively regulates rRNA expression	REACTOME	R-HSA-5250924
Activation of HOX genes during differentiation	REACTOME	R-HSA-5619507
Activation of anterior HOX genes in hindbrain development during early embryogenesis	REACTOME	R-HSA-5617472
TP53 Regulates Transcription of Cell Cycle Genes	REACTOME	R-HSA-6791312
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	REACTOME	R-HSA-6804114
Regulation of TP53 Activity	REACTOME	R-HSA-5633007
Regulation of TP53 Activity through Methylation	REACTOME	R-HSA-6804760
Regulation of TP53 Activity through Acetylation	REACTOME	R-HSA-6804758
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	REACTOME	R-HSA-8864260
Activation of the TFAP2 (AP-2) family of transcription factors	REACTOME	R-HSA-8866907
Deubiquitination	REACTOME	R-HSA-5688426
Metalloprotease DUBs	REACTOME	R-HSA-5689901
PI5P Regulates TP53 Acetylation	REACTOME	R-HSA-6811555

References

Pubmed ID	Year	Title	Citations
34982356	2022	Circ_0001588 Upregulates ERBB4 to Promote Glioma Malignant Progression Through Sponging miR-1281.	3
34982356	2022	Circ_0001588 Upregulates ERBB4 to Promote Glioma Malignant Progression Through Sponging miR-1281.	3
34498706	2021	LncRNA LINC00963 promotes colorectal cancer cell proliferation and metastasis by regulating miR‑1281 and TRIM65.	5
34498706	2021	LncRNA LINC00963 promotes colorectal cancer cell proliferation and metastasis by regulating miR‑1281 and TRIM65.	5
32849308	2020	MicroRNA-1281 as a Novel Circulating Biomarker in Patients With Diabetic Retinopathy.	26
32849308	2020	MicroRNA-1281 as a Novel Circulating Biomarker in Patients With Diabetic Retinopathy.	26
31049960	2019	LncRNA LINC01857 promotes growth, migration, and invasion of glioma by modulating miR-1281/TRIM65 axis.	22
31858553	2019	LncRNA GIHCG regulates microRNA-1281 and promotes malignant progression of breast cancer.	12
31884421	2019	Targeting cyclophilin-D by miR-1281 protects human macrophages from Mycobacterium tuberculosis-induced programmed necrosis and apoptosis.	12
31049960	2019	LncRNA LINC01857 promotes growth, migration, and invasion of glioma by modulating miR-1281/TRIM65 axis.	22
31858553	2019	LncRNA GIHCG regulates microRNA-1281 and promotes malignant progression of breast cancer.	12
31884421	2019	Targeting cyclophilin-D by miR-1281 protects human macrophages from Mycobacterium tuberculosis-induced programmed necrosis and apoptosis.	12
29663357	2018	HPV16 increases the number of migratory cancer stem cells and modulates their miRNA expression profile in oropharyngeal cancer.	15
29663357	2018	HPV16 increases the number of migratory cancer stem cells and modulates their miRNA expression profile in oropharyngeal cancer.	15
27716620	2016	Circulating microRNAs found dysregulated in ex-exposed asbestos workers and pleural mesothelioma patients as potential new biomarkers.	34

Citation

Dessen P

MIR1281 (microRNA 1281)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57556/mir1281-(microrna-1281)

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