Identity
HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
ARAT,ARGP1,DGAT,DIAR7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8694
MIM: 604900
HGNC: 2843
Ensembl: ENSG00000185000
Variants:
dbSNP: 8694
ClinVar: 8694
TCGA: ENSG00000185000
COSMIC: DGAT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185000 | ENST00000332324 | A0A0A0MR74 |
| ENSG00000185000 | ENST00000528718 | O75907 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37973951 | 2024 | Targeting DGAT1 inhibits prostate cancer cells growth by inducing autophagy flux blockage via oxidative stress. | 0 |
| 38500157 | 2024 | The role of DGAT1 and DGAT2 in regulating tumor cell growth and their potential clinical implications. | 2 |
| 37973951 | 2024 | Targeting DGAT1 inhibits prostate cancer cells growth by inducing autophagy flux blockage via oxidative stress. | 0 |
| 38500157 | 2024 | The role of DGAT1 and DGAT2 in regulating tumor cell growth and their potential clinical implications. | 2 |
| 36603576 | 2023 | DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma. | 5 |
| 37516308 | 2023 | Preferential lipolysis of DGAT1 over DGAT2 generated triacylglycerol in Huh7 hepatocytes. | 1 |
| 37779421 | 2023 | The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho-physiological background. | 1 |
| 37820117 | 2023 | Lipid droplets in Zika neuroinfection: Potential targets for intervention? | 0 |
| 36603576 | 2023 | DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma. | 5 |
| 37516308 | 2023 | Preferential lipolysis of DGAT1 over DGAT2 generated triacylglycerol in Huh7 hepatocytes. | 1 |
| 37779421 | 2023 | The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho-physiological background. | 1 |
| 37820117 | 2023 | Lipid droplets in Zika neuroinfection: Potential targets for intervention? | 0 |
| 35764091 | 2022 | An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma. | 10 |
| 35764091 | 2022 | An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma. | 10 |
| 33750350 | 2021 | Up-regulation of DGAT1 in cancer tissues and tumor-infiltrating macrophages influenced survival of patients with gastric cancer. | 8 |
Citation
Dessen P
DGAT1 (diacylglycerol O-acyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2018-07-01
Online version: http://atlasgeneticsoncology.org/gene/57559/dgat1-(diacylglycerol-o-acyltransferase-1)
